1 to 10 of 46 Results
Feb 20, 2023
Reitter, Sonja; Schoelz, Christian; Stoecklin, Georg, 2023, "Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes", https://doi.org/10.11588/data/M5ZUPP, heiDATA, V1
While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of riboso... |
Feb 20, 2023 -
Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes
Adobe PDF - 67.6 KB -
MD5: 52e79d126ebb433a2a3ae58bb0c67beb
|
Feb 20, 2023 -
Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes
Plain Text - 11.8 KB -
MD5: d0b90a51183678ba7c456b04b98943bf
|
Tabular Data - 43.3 KB - 9 Variables, 273 Observations - UNF:6:TuQsCZsNr94F55djEF3jlA==
HeLa cells were SILAC-labeled and treated with DMSO (heavy) or Ro3306 (light, 10 µM) for 4 h. After lysis and disassembly of polysomes in low magnesium buffer, samples were mixed, and ribosomal fractions obtained by sucrose density centrifugation were subjected to Wessel-Flügge p... |
Tabular Data - 453.7 KB - 9 Variables, 2918 Observations - UNF:6:JfKZnmkORxFSPz0dUd0TcQ==
HeLa cells were SILAC-labeled and treated with DMSO (light) or Ro3306 (heavy, 10 µM) for 4 h. After lysis and disassembly of polysomes in low magnesium buffer, samples were mixed, and ribosomal fractions obtained by sucrose density centrifugation were subjected to Wessel-Flügge p... |
Tabular Data - 4.2 KB - 14 Variables, 71 Observations - UNF:6:J05CBEaCX/BstRp7yZfDBA==
The assembly of stress granules (SGs) was monitored in HeLa cells stably expressing GFP-G3BP1 following knock-down of 711 kinases an 256 phosphatases using the Dharmacon siGenome siRNA libraries GU-003505 Human Protein Kinase and GU-003705 Human Protein Phosphatase. Cells were tr... |
Tabular Data - 41.1 KB - 9 Variables, 986 Observations - UNF:6:iGFGYLz0Wtn7xM/H53+5jw==
The assembly of stress granules (SGs) was monitored in HeLa cells stably expressing GFP-G3BP1 following knock-down of 711 kinases an 256 phosphatases using the Dharmacon siGenome siRNA libraries GU-003505 Human Protein Kinase and GU-003705 Human Protein Phosphatase. Cells were tr... |
Feb 20, 2023 -
Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes
Plain Text - 9.8 MB -
MD5: 9bb52f315495efe760b094ae31d556f3
|
Feb 20, 2023 -
Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes
Plain Text - 29.1 MB -
MD5: 6c819e70e5873c0a453b750fc505d93f
|
Feb 20, 2023 -
Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes
Plain Text - 3.3 KB -
MD5: a8de291deaa89661bca9b956f6e9c11f
|