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Image-based screening for stress granule regulators
Jan 7, 2021
Eiermann, Nina; Stoecklin, Georg, 2021, "Image-based screening for stress granule regulators", https://doi.org/10.11588/data/KRPJ9A, heiDATA, V1
The supplied macro provides the opportunity to analyse large-scale image datasets, derived from image-based screening approaches. It can be used as a base for the segmentation of individual cells, referred as regions of interest (ROIs), and the detection and quantification of the...
CDK1 couples proliferation with protein synthesis [Repository Tables R1-R4]
Feb 6, 2020 - SFB 1036
Haneke, Katharina; Stoecklin, Georg, 2020, "CDK1 couples proliferation with protein synthesis [Repository Tables R1-R4]", https://doi.org/10.11588/data/EFHOBZ, heiDATA, V1, UNF:6:+D39RBZQyWVzfn6Sv1nj+w== [fileUNF]
Cell proliferation exerts a high demand on protein synthesis, yet the mechanisms coupling the two processes are not fully understood. A kinase and phosphatase screen for activators of translation, based on the formation of stress granules in human cells, revealed cell cycle-assoc...
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