1 to 2 of 2 Results
Feb 9, 2024
Pham, Truc Lam; Conde González, Marcos Rafael; Fazliev, Sunnatullo; Kishore, Agi; Comba, Peter; Thomas, Franziska, 2024, "Relationship of Thermostability and Binding Affinity in Metal-binding WW-Domain Minireceptors [Research Data]", https://doi.org/10.11588/data/QSJTR0, heiDATA, V1
The design of metallo-miniproteins advances our understanding of the structural and functional roles of metals in proteins. We recently designed a metal-binding WW domain, WW-CA-Nle, which displays three histidine residues on its surface for coordination of divalent metals Ni(II)... |
Jan 19, 2022
Pham, Truc Lam; Kovermann, Michael; Thomas, Franziska, 2022, "Switchable Zinc (II)-Responsive Globular β-Sheet Peptide [Research Data]", https://doi.org/10.11588/data/HV4MJW, heiDATA, V1
The natural function of many proteins depends on their ability to switch their conformation driven by environmental changes. In this work, we present a small, monomeric β-sheet peptide that switches between a molten globule and a folded state through Zn(II) binding. The solvent-e... |