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Aug 15, 2023 - NCT - Section of Translational Medical Ethics
Anger, Michael; Wendelborn, Christian; Schickhardt, Christoph, 2023, "German funders' data sharing policies - A qualitative interview study [interview excerpts]", https://doi.org/10.11588/data/FJAG0X, heiDATA, V1
Background Data sharing is commonly seen as beneficial for science, but is not yet common practice. Research funding agencies are known to play a key role in promoting data sharing, but German funders’ data sharing policies appear to lag behind in international comparison. This s... |
May 9, 2023 - Integrative Virology
Sadhu, Lopamudra; Tsopoulidis, Nikolaos; Hasanuzzaman, Md; Laket, Vibor; Way, Michael; Fackler, Oliver T., 2023, "ARPC5 Isoforms and Their Regulation by Calcium-Cal 1 modulin-N-WASP Drive Distinct Arp2/3-dependent Actin Remodeling Events in CD4 T Cells [Source Data Files]", https://doi.org/10.11588/data/YVYEO8, heiDATA, V2
This dataset contains the source data files of the article 'ARPC5 Isoforms and Their Regulation by Calcium-Cal 1 modulin-N-WASP Drive Distinct Arp2/3-dependent Actin Remodeling Events in CD4 T Cells' by Sadhu et al. pulished in eLife. |
Aug 2, 2022 - NCT - Section of Translational Medical Ethics
Anger, Michael; Wendelborn, Christian; Winkler, Eva; Schickhardt, Christoph, 2022, "Neither Carrots nor Sticks? Challenges surrounding Data Sharing from the Perspective of Research Funding Agencies – A Qualitative Expert Interview Study [Interview Excerpts]", https://doi.org/10.11588/data/M2TSIT, heiDATA, V1
This dataset contains summaries from interviews with data sharing experts from internationa funding agencies on their organisation's data sharing policy. Data Sharing is widely recognised as crucial for accelerating scientific research and improving its quality. However, data sha... |
Kong, Ka-Yiu Edwin; Fischer, Bernd; Meurer, Matthias; Kats, Ilia; Li, Zhaoyan; Rühle, Frank; Barry, Joseph D.; Kirrmaier, Daniel; Chevyreva, Veronika; San Luis, Bryan-Joseph; Costanzo, Michael; Huber, Wolfgang; Andrews, Brenda J.; Boone, Charles; Knop, Michael; Khmelinskii, Anton, 2021, "Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase [Dataset]", https://doi.org/10.11588/data/Q3TSLH, heiDATA, V1
Data accompanying the paper "Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase". |
Apr 6, 2020 - Anders Group
Roider, Tobias; Seufert, Julian; Uvarovskii, Alexey; Frauhammer, Felix; Bordas, Marie; Abedpour, Nima; Stolarczyk, Marta; Mallm, Jan-Philipp; Herbst, Sophie A.; Bruch, Peter-Martin; Balke-Want, Hyatt; Hundemer, Michael; Rippe, Karsten; Goeppert, Benjamin; Seiffert, Martina; Brors, Benedikt; Mechtersheimer, Gunhild; Zenz, Thorsten; Peifer, Martin; Chapuy, Björn; Schlesner, Matthias; Müller-Tidow, Carsten; Fröhling, Stefan; Huber, Wolfgang; Anders, Simon; Sascha Dietrich, 2020, "Dissecting intratumor heterogeneity of nodal B cell lymphomas at transcriptional, genetic, and drug response levels", https://doi.org/10.11588/data/VRJUNV, heiDATA, V1, UNF:6:AlKw3YwYZ82Ty5CxnC4D5w== [fileUNF]
Tumour heterogeneity encompasses both the malignant cells and their microenvironment. While heterogeneity between individual patients is known to affect the efficacy of cancer therapy, most personalized treatment approaches do not account for intratumor heterogeneity. We addresse... |
Feb 6, 2020 - SFB 1036
Haneke, Katharina; Stoecklin, Georg, 2020, "CDK1 couples proliferation with protein synthesis [Repository Tables R1-R4]", https://doi.org/10.11588/data/EFHOBZ, heiDATA, V1, UNF:6:+D39RBZQyWVzfn6Sv1nj+w== [fileUNF]
Cell proliferation exerts a high demand on protein synthesis, yet the mechanisms coupling the two processes are not fully understood. A kinase and phosphatase screen for activators of translation, based on the formation of stress granules in human cells, revealed cell cycle-assoc... |
May 28, 2019 - KnopLab
Buchmuller, Benjamin C; Herbst, Konrad; Meurer, Matthias; Kirrmaier, Daniel; Sass, Ehud; Levy, Emmanuel D; Knop, Michael, 2019, "Pooled clone collections by multiplexed CRISPR-Cas12a-assisted gene tagging in yeast [Dataset]", https://doi.org/10.11588/data/L45TRX, heiDATA, V2
Data accompanying the paper "Pooled clone collections by multiplexed CRISPR-Cas12a-assisted gene tagging in yeast" by Buchmuller and Herbst et al, 2019, Nat Communications. This contains raw NGS data for all genotyping analysis in the publication as well as the source code of the... |
Constantinou, Iordania; Jendrusch, Michael; Aspert, Théo; Görlitz, Frederik; Schulze, André; Charvin, Gilles; Knop, Michael, 2018, "3D Focusing in Simple Microfluidic Devices for Continuous-flow Single-cell Imaging [data set]", https://doi.org/10.11588/data/L5J7WO, heiDATA, V1
Accompanying data for the manuscript "3D Focusing in Simple Microfluidic Devices for Continuous-flow Single-cell Imaging". |
Nov 27, 2018 - Diagnostic and Interventional Radiology
Triphan, Simon, 2018, "Perfusion quantification data for "Towards Quantitative Perfusion MRI of the Lung in COPD: The Problem of Short-Term Repeatability"", https://doi.org/10.11588/data/ZPEZPX, heiDATA, V1, UNF:6:SE0iKbhWdsMOrcUkd706AA== [fileUNF]
ABSTRACT Purpose 4D perfusion magnetic resonance imaging (MRI) with intravenous injection of contrast agent allows for a radiation-free assessment of regional lung function. It is therefore a valuable method to monitor response to treatment in patients with chronic obstructive pu... |
Cleo-Aron Weis, 2018, "Histopathology of thymectomy specimens from the MGTX-trial", https://doi.org/10.11588/data/NWE2JJ, heiDATA, V1, UNF:6:Od2UlnHG3ctanb4ikzIx4g== [fileUNF]
Background: The thymectomy specimens from the “thymectomy trial in non-thymomatous myasthenia gravis patients receiving prednisone therapy” (MGTX) [1] underwent rigid and comprehensive work-up, which results in a unique, spatially mapped dataset. Fig. 1 Specimen work-up: Work-up... |
