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DNA microbeads for spatio-temporally controlled morphogen release within organoids [Research data]
Aug 30, 2024 - Göpfrich Group - Biophysical Engineering of Life
Walther, Tobias; Afting, Cassian; Drozdowski, Oliver M.; Schlagheck, Christina; Schwarz, Ulrich S.; Wittbrodt, Joachim; Göpfrich, Kerstin, 2024, "DNA microbeads for spatio-temporally controlled morphogen release within organoids [Research data]", https://doi.org/10.11588/data/T87EPK, heiDATA, V1
Organoids have proven to be powerful in vitro model systems that mimic features of the corresponding tissue in vivo. However, across tissue types and species, organoids still often fail to reach full maturity and function because biochemical cues cannot be provided from within th...
Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]
Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]
Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...
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