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1 to 4 of 4 Results
DNA microbeads for spatio-temporally controlled morphogen release within organoids [Research data]
Aug 30, 2024
Walther, Tobias; Afting, Cassian; Drozdowski, Oliver M.; Schlagheck, Christina; Schwarz, Ulrich S.; Wittbrodt, Joachim; Göpfrich, Kerstin, 2024, "DNA microbeads for spatio-temporally controlled morphogen release within organoids [Research data]", https://doi.org/10.11588/data/T87EPK, heiDATA, V1
Organoids have proven to be powerful in vitro model systems that mimic features of the corresponding tissue in vivo. However, across tissue types and species, organoids still often fail to reach full maturity and function because biochemical cues cannot be provided from within th...
Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]
Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]
Feb 16, 2024
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...
Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]
Feb 28, 2022
Goepfrich, Kerstin; Walther, Tobias, 2022, "Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]", https://doi.org/10.11588/data/MKOC9S, heiDATA, V1
In the pursuit to produce functioning synthetic cells from the bottom up, DNA nanotechnology has proven to be a powerful tool. However, the crowded yet highly organized arrangement in living cells, bridging from the nano- to the micron-scale, remains challenging to recreate with...
Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]
Nov 30, 2021
Abele, Tobias; Messer, Tobias; Jahnke, Kevin; Hippler, Marc; Bastmeyer, Martin; Wegener, Martin; Goepfrich, Kerstin, 2021, "Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]", https://doi.org/10.11588/data/PUKJCV, heiDATA, V1
Towards the ambitious goal of manufacturing synthetic cells from the bottom up, various cellular components have already been reconstituted inside of lipid vesicles. However, the deterministic positioning of these components inside the compartment has remained elusive. Here, by u...
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