1 to 7 of 7 Results
Aug 30, 2024 - Göpfrich Group - Biophysical Engineering of Life
Walther, Tobias; Afting, Cassian; Drozdowski, Oliver M.; Schlagheck, Christina; Schwarz, Ulrich S.; Wittbrodt, Joachim; Göpfrich, Kerstin, 2024, "DNA microbeads for spatio-temporally controlled morphogen release within organoids [Research data]", https://doi.org/10.11588/data/T87EPK, heiDATA, V1
Organoids have proven to be powerful in vitro model systems that mimic features of the corresponding tissue in vivo. However, across tissue types and species, organoids still often fail to reach full maturity and function because biochemical cues cannot be provided from within th... |
Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a... |
Mar 24, 2023 - HITS MBM
Rennekamp, Benedikt; Gräter, Frauke, 2023, "Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data]", https://doi.org/10.11588/data/HJ6SVM, heiDATA, V1, UNF:6:Da6omTKjrSvNcDwyJxuHOg== [fileUNF]
This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related pu... |
Nov 8, 2022
Data publications from the the Molecular Biomechanics (MBM) group at HITS. Shareholders of HITS are the “HITS-Stiftung”, Heidelberg University and the Karlsruhe Institute of Technology (KIT) |
Feb 28, 2022 - Göpfrich Group - Biophysical Engineering of Life
Goepfrich, Kerstin; Walther, Tobias, 2022, "Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]", https://doi.org/10.11588/data/MKOC9S, heiDATA, V1
In the pursuit to produce functioning synthetic cells from the bottom up, DNA nanotechnology has proven to be a powerful tool. However, the crowded yet highly organized arrangement in living cells, bridging from the nano- to the micron-scale, remains challenging to recreate with... |
Nov 30, 2021
The Göpfrich Group is located at at the Max Planck Institute for Medical Research and part of the Cluster of Excellence "3D Matter Made to Order". |
May 14, 2021
Data publications from the Cluster of Excellence 3D Matter Made to Order (3DMM2O). The Cluster is a collaboration of Karlsruhe Institute of Technology (KIT) and Heidelberg University. It pursues an interdisciplinary approach through conjunction of natural, engineering, and social... |