1 to 7 of 7 Results
Jun 13, 2024 - AG Wittbrodt
Afting, Cassian; Mainik, Philipp; Vazquez-Martel, Clara; Abele, Tobias; Kaul, Verena; Kale, Girish; Göpfrich, Kerstin; Lemke, Steffen; Blasco, Eva; Wittbrodt, Joachim, 2024, "Minimal-Invasive 3D Laser Printing of Microimplants in Organismo [data]", https://doi.org/10.11588/data/MVBFOY, heiDATA, V1
Multi-photon 3D laser printing has gathered much attention in recent years as a means of manufacturing biocompatible scaffolds that can modify and guide cellular behavior in vitro. However, in vivo tissue engineering efforts have been limited so far to the implantation of beforeh... |
May 1, 2024
Taale, Mohammadreza; Schmidt, Målin; Taheri, Fereydoon; Timmermann, Michael; Selhuber-Unkel, Christine, 2024, "A Minimalistic, Synthetic Cell-Inspired Metamaterial for Enabling Reversible Strain-Stiffening [data]", https://doi.org/10.11588/data/MNMLVX, heiDATA, V2
Strain-stiffening, i.e. the nonlinear stiffening of a material in response to a strain, is an intrinsic feature of many biological systems, including skin, blood vessels, and single cells. To avoid a mismatch in mechanical properties, synthetic materials in contact with such biol... |
Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a... |
Feb 28, 2022 - Göpfrich Group - Biophysical Engineering of Life
Goepfrich, Kerstin; Walther, Tobias, 2022, "Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]", https://doi.org/10.11588/data/MKOC9S, heiDATA, V1
In the pursuit to produce functioning synthetic cells from the bottom up, DNA nanotechnology has proven to be a powerful tool. However, the crowded yet highly organized arrangement in living cells, bridging from the nano- to the micron-scale, remains challenging to recreate with... |
Nov 30, 2021 - Göpfrich Group - Biophysical Engineering of Life
Abele, Tobias; Messer, Tobias; Jahnke, Kevin; Hippler, Marc; Bastmeyer, Martin; Wegener, Martin; Goepfrich, Kerstin, 2021, "Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]", https://doi.org/10.11588/data/PUKJCV, heiDATA, V1
Towards the ambitious goal of manufacturing synthetic cells from the bottom up, various cellular components have already been reconstituted inside of lipid vesicles. However, the deterministic positioning of these components inside the compartment has remained elusive. Here, by u... |
Sep 23, 2021
de Buhr, Svenja; Gräter, Frauke, 2021, "Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data]", https://doi.org/10.11588/data/3NKHAY, heiDATA, V1
This dataset contains input structures and parameters for coarse-grained molecular dynamics simulation of SAS-6 protein oligomers as well as post-processing files and analysis scripts. Abstract of related publication: Discovering mechanisms governing organelle assembly is a funda... |
Jul 6, 2021 - AG Wittbrodt
Zilova, Lucie; Weinhardt, Venera; Tavhelidse, Tinatini; Schlagheck, Christina; Thumberger, Thomas; Wittbrodt, Joachim, 2021, "Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development - in vivo imaging of OV formation", https://doi.org/10.11588/data/AOSUS8, heiDATA, V1
Development of a functional retina is accompanied by several morphological events transitions that ultimately result in the formation of a functional retina. One of them is the formation of the OV. When fish-derived organoids were generated with reduced cell-seeding density by 50... |