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1 to 10 of 34 Results
Oct 15, 2018 - Statistical Genetics
Kabisch, Maria ; Hamann, Ute; Lorenzo Bermejo, Justo, 2018, "Imputation of Missing Genotypes within LD-Blocks Relying on the Basic Coalescent and Beyond [Source Code]", https://doi.org/10.11588/data/X9UEHB, heiDATA, V1
Background Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study...
Oct 15, 2018 - Statistical Genetics
Peil, Barbara; Kabisch, Maria; Fischer, Christine; Hamann, Ute; Lorenzo Bermejo, Justo, 2018, "Tailored Selection of Study Individuals to be Sequenced in Order to Improve the Accuracy of Genotype Imputation [Source Code]", https://doi.org/10.11588/data/TT4VM3, heiDATA, V1
The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombi...
Oct 15, 2018 - Statistical Genetics
Kesselmeier, Miriam; Lorenzo Bermejo, Justo, 2018, "Robust logistic regression to narrow down the winner's curse for rare and recessive susceptibility variants [Source Code]", https://doi.org/10.11588/data/0Z7H1X, heiDATA, V1
Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unus...
Oct 5, 2018 - Statistical Genetics
Lorenzo Bermejo, Justo; Boekstegers, Felix ; González Silos, Rosa ; Marcelain, Katherine; Baez Benavides, Pablo; Barahona Ponce, Carol; Müller, Bettina; Ferreccio, Catterina; Koshiol, Jill; Fischer, Christine; Peil, Barbara; Sinsheimer,Janet; Fuentes Guajardo,Macarena; Barajas, Olga; Gonzalez-Jose, Rolando; Bedoya, Gabriel; Cátira Bortolini, Maria; Canizales-Quinteros,Samuel; Gallo, Carla; Ruiz Linares, Andres; Rothhammer, Francisco, 2018, "Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile [Dataset]", https://doi.org/10.11588/data/IDSI88, heiDATA, V1
Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and disease prevention. Here we investigate possible association...
Statistical Genetics(Heidelberg University - Medical Faculty Heidelberg)
Oct 5, 2018
Data publications from the Statistical Genetics Group at Heidelberg University's Institute of Medical Biometry and Informatics.
Oct 5, 2018 - Statistical Genetics
Hemminki, Kari ; Lorenzo Bermejo, Justo, 2018, "Calculation of Population attributable fraction Familial relative risk and Statistical power", https://doi.org/10.11588/data/1KJEDB, heiDATA, V1
Candidate gene studies have become very popular but some of their implicit constraints, such as the familial risk and the population attributable fraction (PAF) conferred by the gene under study, are poorly understood. We model here these parameters for susceptibility genes in te...
Aug 20, 2018 - Institute of Pathology Mannheim
Weis, Cleo-Aron, 2018, "Automatic evaluation of tumour budding in immunohistochemically stained colorectal carcinomas and correlation to clinical outcome [Dataset]", https://doi.org/10.11588/data/XJAOC4, heiDATA, V1
Data used for the implementation of the proposed tumor budding detection In the publication “Automatic evaluation of tumour budding in immunohistochemically stained colorectal carcinomas and correlation to clinical outcome” we described a multistep approach to detect tumor buds i...
Jul 18, 2018 - Propylaeum
Küster, Hansjörg, 2018, "Mittelalterliche Pflanzenreste von der Marktstätte und Brotlaube in Konstanz [Dataset]", https://doi.org/10.11588/data/ARWJHB, heiDATA, V1
During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices...
Jun 8, 2018 - Diagnostic and Interventional Radiology
Triphan, Simon; Biederer, Jürgen; Burmester, Kerstin; Fellhauer, Iven; Vogelmeier, Claus; Jörres, Rudolf; Kauczor, Hans-Ulrich; Heußel, Claus; Wielpütz, Mark; Jobst, Bertram, 2018, "Raw data and analysis scripts for "Design and application of an MR reference phantom for multicentre lung imaging trials"", https://doi.org/10.11588/data/FHOCRZ, heiDATA, V1
This dataset contains all MRI phantom data discussed in the related publication as well as the python scripts used to analyse them. The format is DICOM files, where institution names and adresses have been anonymized. Abstract Introduction: As there is an increasing number of mul...
Diagnostic and Interventional Radiology (Heidelberg University - Medical Faculty Heidelberg)
Jun 8, 2018
Data publications from the Department for Diagnostic and Interventional Radiology at the Medical Faculty Heidelberg (Heidelberg University).
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