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Subject: Medicine, Health and Life Sciences Subject: Physics

11 to 14 of 14 Results

Dose Enhancement Effects of Gold Nanoparticles Specifically Targeting RNA in Breast Cancer Cells [Dataset] Dec 4, 2017 - Experimental Biophysics Hildenbrand, Georg; Metzler, Philipp; Pilarczyk, Goetz; Bobu, Vladimir; Hosser, Hiltraud; Fleckenstein, Jens; Krufczik, Matthias; Bestvater, Felix; Wenz, Frederik; Hausmann, Michael, 2017, "Dose Enhancement Effects of Gold Nanoparticles Specifically Targeting RNA in Breast Cancer Cells [Dataset]", https://doi.org/10.11588/data/N8NHE2, heiDATA, V1 Localization microscopy has shown to be capable of systematic investigations on the arrangement and counting of cellular uptake of gold nanoparticles (GNP) with nanometer resolution. In this article, we show that the application of specially modified RNA targeting gold nanopartic...
Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset] Oct 16, 2014 - Theoretical Physics Jerabek, Hansjörg; Tark-Dame, Mariliis; Manders, Erik M. M.; Heermann, Dieter W.; van Driel, Roel, 2014, "Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset]", https://doi.org/10.11588/data/10028, heiDATA, V4 Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction.
Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data] Mar 24, 2023 - HITS MBM Rennekamp, Benedikt; Gräter, Frauke, 2023, "Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data]", https://doi.org/10.11588/data/HJ6SVM, heiDATA, V1, UNF:6:Da6omTKjrSvNcDwyJxuHOg== [fileUNF] This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related pu...
Allosteric Activation of Vinculin by Talin [data] Jun 1, 2023 - HITS MBM Gräter, Frauke; Franz, Florian; Winograd-Katz, Sabina; Tapia-Rojo, Rafael; Boujemaa-Paterski, Rajaa; Li, Wenhong; Unger, Tamar; Albeck, Shira; Aponte-Santamaria, Camilo; Garcia-Manyes, Sergi; Medalia, Ohad; Geiger, Benny, 2023, "Allosteric Activation of Vinculin by Talin [data]", https://doi.org/10.11588/data/WZDKT6, heiDATA, V1, UNF:6:32j0OWUdxRAbsyCMzwdFcQ== [fileUNF] The talin-vinculin axis is a key mechanosensing component of cellular focal adhesions. How talin and vinculin respond to forces and regulate one another remains unclear. By combining single molecule magnetic tweezer experiments, Molecular Dynamics simulations, actin bundling assa...

Dose Enhancement Effects of Gold Nanoparticles Specifically Targeting RNA in Breast Cancer Cells [Dataset]

Dec 4, 2017 - Experimental Biophysics

Hildenbrand, Georg; Metzler, Philipp; Pilarczyk, Goetz; Bobu, Vladimir; Hosser, Hiltraud; Fleckenstein, Jens; Krufczik, Matthias; Bestvater, Felix; Wenz, Frederik; Hausmann, Michael, 2017, "Dose Enhancement Effects of Gold Nanoparticles Specifically Targeting RNA in Breast Cancer Cells [Dataset]", https://doi.org/10.11588/data/N8NHE2, heiDATA, V1

Localization microscopy has shown to be capable of systematic investigations on the arrangement and counting of cellular uptake of gold nanoparticles (GNP) with nanometer resolution. In this article, we show that the application of specially modified RNA targeting gold nanopartic...

Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset]

Oct 16, 2014 - Theoretical Physics

Jerabek, Hansjörg; Tark-Dame, Mariliis; Manders, Erik M. M.; Heermann, Dieter W.; van Driel, Roel, 2014, "Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset]", https://doi.org/10.11588/data/10028, heiDATA, V4

Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction.

Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data]

Mar 24, 2023 - HITS MBM

Rennekamp, Benedikt; Gräter, Frauke, 2023, "Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data]", https://doi.org/10.11588/data/HJ6SVM, heiDATA, V1, UNF:6:Da6omTKjrSvNcDwyJxuHOg== [fileUNF]

This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related pu...

Allosteric Activation of Vinculin by Talin [data]

Jun 1, 2023 - HITS MBM

Gräter, Frauke; Franz, Florian; Winograd-Katz, Sabina; Tapia-Rojo, Rafael; Boujemaa-Paterski, Rajaa; Li, Wenhong; Unger, Tamar; Albeck, Shira; Aponte-Santamaria, Camilo; Garcia-Manyes, Sergi; Medalia, Ohad; Geiger, Benny, 2023, "Allosteric Activation of Vinculin by Talin [data]", https://doi.org/10.11588/data/WZDKT6, heiDATA, V1, UNF:6:32j0OWUdxRAbsyCMzwdFcQ== [fileUNF]

The talin-vinculin axis is a key mechanosensing component of cellular focal adhesions. How talin and vinculin respond to forces and regulate one another remains unclear. By combining single molecule magnetic tweezer experiments, Molecular Dynamics simulations, actin bundling assa...

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