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1 to 10 of 17 Results
Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...
Oct 5, 2018 - Statistical Genetics
Lorenzo Bermejo, Justo; Boekstegers, Felix; González Silos, Rosa; Marcelain, Katherine; Baez Benavides, Pablo; Barahona Ponce, Carol; Müller, Bettina; Ferreccio, Catterina; Koshiol, Jill; Fischer, Christine; Peil, Barbara; Sinsheimer,Janet; Fuentes Guajardo,Macarena; Barajas, Olga; Gonzalez-Jose, Rolando; Bedoya, Gabriel; Cátira Bortolini, Maria; Canizales-Quinteros,Samuel; Gallo, Carla; Ruiz Linares, Andres; Rothhammer, Francisco, 2018, "Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile [Dataset]", https://doi.org/10.11588/data/IDSI88, heiDATA, V1
Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and disease prevention. Here we investigate possible association...
Dec 19, 2023 - Forschungsgruppe AG Nikendei
Tambini Stollwerck, Estella; Rollmann, Ivo; Friederich, Hans-Christoph; Nikendei, Christoph, 2023, "Screening for Human Trafficking among Refugees in Germany [Data and Analysis]", https://doi.org/10.11588/data/DUNN8C, heiDATA, V2, UNF:6:R3G0Z5d0LrKFPtVc+7f0yA== [fileUNF]
Background: Human trafficking occurs all over the world and its true extent is still unknown. What we know is that the actual number of trafficked persons is significantly higher than the number of registered cases in Europe or anywhere else. Human trafficking is particularly lik...
Jun 8, 2018 - Diagnostic and Interventional Radiology
Triphan, Simon; Biederer, Jürgen; Burmester, Kerstin; Fellhauer, Iven; Vogelmeier, Claus; Jörres, Rudolf; Kauczor, Hans-Ulrich; Heußel, Claus; Wielpütz, Mark; Jobst, Bertram, 2018, "Raw data and analysis scripts for "Design and application of an MR reference phantom for multicentre lung imaging trials"", https://doi.org/10.11588/data/FHOCRZ, heiDATA, V1
This dataset contains all MRI phantom data discussed in the related publication as well as the python scripts used to analyse them. The format is DICOM files, where institution names and adresses have been anonymized. Abstract Introduction: As there is an increasing number of mul...
Feb 28, 2022 - Göpfrich Group - Biophysical Engineering of Life
Goepfrich, Kerstin; Walther, Tobias, 2022, "Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]", https://doi.org/10.11588/data/MKOC9S, heiDATA, V1
In the pursuit to produce functioning synthetic cells from the bottom up, DNA nanotechnology has proven to be a powerful tool. However, the crowded yet highly organized arrangement in living cells, bridging from the nano- to the micron-scale, remains challenging to recreate with...
Feb 23, 2023 - Heidelberg Pain Consortium - SFB 1158
Oswald, Manfred Josef; Beretta, Carlo Antonio; Stegemann, Alina; Han, Yechao; Kuner, Rohini, 2023, "Prefrontal engrams of long-term fear memory and pain", https://doi.org/10.11588/data/VEEIDP, heiDATA, V1, UNF:6:QT9272Lmh0bGgVxcezQ+yw== [fileUNF]
This dataset contains electrophysiological spike time data and associated analysis procedures as well as image analysis scripts reported in Stegemann et al. Prefrontal engrams of long-term fear memory perpetuate pain perception. Nature Neuroscience (2023). Abstract: A painful epi...
Dec 14, 2023 - AG Lindner - Experimental Anesthesiology
Lindner, Holger A.; Schäfer, Noah; Hahn, Bianka; Schefzik, Roman; Velásquez, Sonia Y.; Schulte, Jutta; Fudrer, Tanja; Centner, Franz-Simon; Schöttler, Jochen J.; Himmelhan, Bianca S.; Sturm, Timo; Thiel, Manfred; Schneider-Lindner, verena; Coulibaly, Anna, 2023, "Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data]", https://doi.org/10.11588/data/4Z4CY3, heiDATA, V1, UNF:6:yxeE0siVL+Y/KFepT7ueug== [fileUNF]
Background: Pneumonia develops frequently after major surgery and polytrauma, and in the presence of systemic inflammatory response syndrome (SIRS) and organ dysfunction. Immune checkpoints balance self-tolerance and immune activation. Altered checkpoint blood levels were reporte...
Nov 27, 2018 - Diagnostic and Interventional Radiology
Triphan, Simon, 2018, "Perfusion quantification data for "Towards Quantitative Perfusion MRI of the Lung in COPD: The Problem of Short-Term Repeatability"", https://doi.org/10.11588/data/ZPEZPX, heiDATA, V1, UNF:6:SE0iKbhWdsMOrcUkd706AA== [fileUNF]
ABSTRACT Purpose 4D perfusion magnetic resonance imaging (MRI) with intravenous injection of contrast agent allows for a radiation-free assessment of regional lung function. It is therefore a valuable method to monitor response to treatment in patients with chronic obstructive pu...
Jan 26, 2024 - Siemens Lab
Marty-Lombardi, Sebastián; Lu, Shiying; Ambroziak, Wojciech; Schrenk-Siemens, Katrin; Wang, Jialin; DePaoli-Roach, Anna A.; Hagenston, Anna M.; Wende, Hagen; Tappe-Theodor, Anke; Simonetti, Manuela; Bading, Hilmar; Okun, Jürgen G.; Kuner, Rohini; Fleming, Thomas; Siemens, Jan, 2024, "Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain [data]", https://doi.org/10.11588/data/AMDH7G, heiDATA, V1
Long-lasting pain stimuli can trigger maladaptive changes in the spinal cord, reminiscent of plasticity associated with memory formation. Metabolic coupling between astrocytes and neurons has been implicated in neuronal plasticity and memory formation in the CNS, but neither its...
Mar 29, 2022 - Theoretical Physics
Li, Kunhe; Oiwa, Nestor N.; Mishra, Sujeet K.; Heermann, Dieter W., 2022, "Inter-Nucleosomal Potentials from Nucleosomal Positioning Data [Research Data]", https://doi.org/10.11588/data/H3KPEU, heiDATA, V1
This dataset accompanies the paper "Inter-Nucleosomal Potentials from Nucleosomal Positioning Data." In this paper, a systematic method to develop inter-nucleosomal potentials between nucleosomes along a chromosome is focused. To this purpose, a modified Lennard-Jones potential i...
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