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1 to 10 of 15 Results

Screening for Human Trafficking among Refugees in Germany [Data and Analysis] Dec 19, 2023 - Forschungsgruppe AG Nikendei Tambini Stollwerck, Estella; Rollmann, Ivo; Friederich, Hans-Christoph; Nikendei, Christoph, 2023, "Screening for Human Trafficking among Refugees in Germany [Data and Analysis]", https://doi.org/10.11588/data/DUNN8C, heiDATA, V2, UNF:6:R3G0Z5d0LrKFPtVc+7f0yA== [fileUNF] Background: Human trafficking occurs all over the world and its true extent is still unknown. What we know is that the actual number of trafficked persons is significantly higher than the number of registered cases in Europe or anywhere else. Human trafficking is particularly lik...
Diagnostic performance of host protein signatures as a triage test for active pulmonary TB [data] Sep 21, 2023 - Division of Infectious Disease and Tropical Medicine FIND, Geneva, Switzerland, 2023, "Diagnostic performance of host protein signatures as a triage test for active pulmonary TB [data]", https://doi.org/10.11588/data/CYYNBA, heiDATA, V1 The current four symptom screen recommended by the WHO is widely used as screen to initiate diagnostic testing for active pulmonary tuberculosis (TB), yet the performance is poor especially when TB prevalence is low. In contrast, more sensitive molecular tests are less suitable f...
Implementation of deep learning in liver pathology optimizes diagnosis of benign lesions and adenocarcinoma metastasis [data] Jul 7, 2023 - AG Computational Diagnostic Kriegsmann, Mark; Kriegsmann, Katharina; Steinbuss, Georg; Zgorzelski, Christiane; Albrecht, Thomas; Heinrich, Stefan; Farkas, Stefan; Roth, Wilfried; Hausen, Anne; Gaida, Matthias M., 2023, "Implementation of deep learning in liver pathology optimizes diagnosis of benign lesions and adenocarcinoma metastasis [data]", https://doi.org/10.11588/data/YAZWJW, heiDATA, V1, UNF:6:gpQyF/jPYXHbW7GvjUboGQ== [fileUNF] Differentiation of neoplastic and non-neoplastic liver lesions using routine histological tissue sections can be challenging. Correct classification is paramount to forecast prognosis and to select the correct therapy. Deep learning algorithms have recently been suggested to supp...
Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections [data] Mar 2, 2023 - AG Computational Diagnostic Kriegsmann, Katharina; Lobers, Fritjof; Zgorzelski, Christiane; Kriegsmann, Jörg; Meliß, Rolf Rüdiger; Sack, Ulrich; Steinbuss,Georg; Kriegsmann,Mark, 2023, "Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections [data]", https://doi.org/10.11588/data/7QCR8S, heiDATA, V1 Basal cell carcinoma (BCC), squamous cell carcinoma (SqCC) and melanoma are among the most common cancer types. Correct diagnosis based on histological evaluation after biopsy or excision is paramount for adequate therapy stratification. Deep learning on histological slides has b...
Prediction and Comparative Analysis of CTCF Binding Sites based on a First Principle Approach [Research Data] Mar 7, 2022 - Theoretical Physics Li, Kunhe; Oiwa, Nestor Norio; Cordeiro, Claudette E.; Heermann, Dieter W., 2022, "Prediction and Comparative Analysis of CTCF Binding Sites based on a First Principle Approach [Research Data]", https://doi.org/10.11588/data/RDISCE, heiDATA, V1 The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. T...
Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: an updated systematic review and meta-analysis with meta regression analyzing influencing factors [Research Data] Feb 25, 2022 - Division of Infectious Disease and Tropical Medicine Brümmer, Lukas E.; Katzenschlager, Stephan; McGrath, Sean; Schmitz, Stephani; Gaeddert, Mary; Erdmann, Christian; Bota, Marc; Grilli, Maurizio; Larmann, Jan; Weigand, Markus A.; Pollock, Nira R.; Macé, Aurélien; Erkosar, Berra; Carmona, Sergio; Sacks, Jilian A.; Ongarello, Stefano; Denkinger, Claudia M., 2022, "Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: an updated systematic review and meta-analysis with meta regression analyzing influencing factors [Research Data]", https://doi.org/10.11588/data/T3MIB0, heiDATA, V1 Background Comprehensive information about the accuracy of antigen rapid diagnostic tests (Ag-RDTs) for SARS-CoV-2 is essential to guide public health decision makers in choosing the best tests and testing policies. In August 2021, we published a systematic review and meta-analys...
Assessment of glomerular morphological patterns by deep learning algorithms [Research Data] Feb 7, 2022 - Institute of Pathology Mannheim Weis, Cleo-Aron, 2022, "Assessment of glomerular morphological patterns by deep learning algorithms [Research Data]", https://doi.org/10.11588/data/JWZ2CK, heiDATA, V1 Test data and models to the paper "Assessment of glomerular morphological patterns by deep learning algorithms". Different, from other groups, defined CNN-models (saved as .pt-files) are trained to identify nine predefined patterns of glomerular changes. The models are: AlexNet [...
The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data] Aug 24, 2021 - Global Health and Economics Kohler, Stefan; Ndungwani, Rumbidzai; Burgert, Mark; Sibandze, Dumile; Matse, Sindy; Hettema, Anita, 2021, "The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]", https://doi.org/10.11588/data/KXTQTZ, heiDATA, V1 HIV treatment and prevention as well as other chronic disease care can require regular kidney function assessment based on a creatinine test. To assess the costs of creatinine testing in a public health care system, we conducted activity-based costing during a HIV pre-exposure pr...
Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset] Jul 27, 2021 - Institute of Pathology Mannheim Runz, Marlen; Weis, Cleo-Aron, 2021, "Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset]", https://doi.org/10.11588/data/8LKEZF, heiDATA, V1 Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University....
Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data] Jul 16, 2021 - Division of Infectious Disease and Tropical Medicine Krüger, Lisa Johanna; Tobian, Frank; Gaeddert, Mary; Lainati, Federica; Klein, Julian A.F.; Schnitzler, Paul; Lindner, Andreas K.; Mockenhaupt, Frank P.; Nikolai, Olga; Seybold, Joachim; Corman, Victor M.; Drosten, Christian; Knorr, Britta; Welker, Andreas; de Vos, Margaretha; Sacks, Jilian A.; Denkinger, Claudia M., 2021, "Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data]", https://doi.org/10.11588/data/D0ACC0, heiDATA, V1 This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab...

Screening for Human Trafficking among Refugees in Germany [Data and Analysis]

Dec 19, 2023 - Forschungsgruppe AG Nikendei

Tambini Stollwerck, Estella; Rollmann, Ivo; Friederich, Hans-Christoph; Nikendei, Christoph, 2023, "Screening for Human Trafficking among Refugees in Germany [Data and Analysis]", https://doi.org/10.11588/data/DUNN8C, heiDATA, V2, UNF:6:R3G0Z5d0LrKFPtVc+7f0yA== [fileUNF]

Background: Human trafficking occurs all over the world and its true extent is still unknown. What we know is that the actual number of trafficked persons is significantly higher than the number of registered cases in Europe or anywhere else. Human trafficking is particularly lik...

Diagnostic performance of host protein signatures as a triage test for active pulmonary TB [data]

Sep 21, 2023 - Division of Infectious Disease and Tropical Medicine

FIND, Geneva, Switzerland, 2023, "Diagnostic performance of host protein signatures as a triage test for active pulmonary TB [data]", https://doi.org/10.11588/data/CYYNBA, heiDATA, V1

The current four symptom screen recommended by the WHO is widely used as screen to initiate diagnostic testing for active pulmonary tuberculosis (TB), yet the performance is poor especially when TB prevalence is low. In contrast, more sensitive molecular tests are less suitable f...

Implementation of deep learning in liver pathology optimizes diagnosis of benign lesions and adenocarcinoma metastasis [data]

Jul 7, 2023 - AG Computational Diagnostic

Kriegsmann, Mark; Kriegsmann, Katharina; Steinbuss, Georg; Zgorzelski, Christiane; Albrecht, Thomas; Heinrich, Stefan; Farkas, Stefan; Roth, Wilfried; Hausen, Anne; Gaida, Matthias M., 2023, "Implementation of deep learning in liver pathology optimizes diagnosis of benign lesions and adenocarcinoma metastasis [data]", https://doi.org/10.11588/data/YAZWJW, heiDATA, V1, UNF:6:gpQyF/jPYXHbW7GvjUboGQ== [fileUNF]

Differentiation of neoplastic and non-neoplastic liver lesions using routine histological tissue sections can be challenging. Correct classification is paramount to forecast prognosis and to select the correct therapy. Deep learning algorithms have recently been suggested to supp...

Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections [data]

Mar 2, 2023 - AG Computational Diagnostic

Kriegsmann, Katharina; Lobers, Fritjof; Zgorzelski, Christiane; Kriegsmann, Jörg; Meliß, Rolf Rüdiger; Sack, Ulrich; Steinbuss,Georg; Kriegsmann,Mark, 2023, "Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections [data]", https://doi.org/10.11588/data/7QCR8S, heiDATA, V1

Basal cell carcinoma (BCC), squamous cell carcinoma (SqCC) and melanoma are among the most common cancer types. Correct diagnosis based on histological evaluation after biopsy or excision is paramount for adequate therapy stratification. Deep learning on histological slides has b...

Prediction and Comparative Analysis of CTCF Binding Sites based on a First Principle Approach [Research Data]

Mar 7, 2022 - Theoretical Physics

Li, Kunhe; Oiwa, Nestor Norio; Cordeiro, Claudette E.; Heermann, Dieter W., 2022, "Prediction and Comparative Analysis of CTCF Binding Sites based on a First Principle Approach [Research Data]", https://doi.org/10.11588/data/RDISCE, heiDATA, V1

The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. T...

Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: an updated systematic review and meta-analysis with meta regression analyzing influencing factors [Research Data]

Feb 25, 2022 - Division of Infectious Disease and Tropical Medicine

Brümmer, Lukas E.; Katzenschlager, Stephan; McGrath, Sean; Schmitz, Stephani; Gaeddert, Mary; Erdmann, Christian; Bota, Marc; Grilli, Maurizio; Larmann, Jan; Weigand, Markus A.; Pollock, Nira R.; Macé, Aurélien; Erkosar, Berra; Carmona, Sergio; Sacks, Jilian A.; Ongarello, Stefano; Denkinger, Claudia M., 2022, "Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: an updated systematic review and meta-analysis with meta regression analyzing influencing factors [Research Data]", https://doi.org/10.11588/data/T3MIB0, heiDATA, V1

Background Comprehensive information about the accuracy of antigen rapid diagnostic tests (Ag-RDTs) for SARS-CoV-2 is essential to guide public health decision makers in choosing the best tests and testing policies. In August 2021, we published a systematic review and meta-analys...

Assessment of glomerular morphological patterns by deep learning algorithms [Research Data]

Feb 7, 2022 - Institute of Pathology Mannheim

Weis, Cleo-Aron, 2022, "Assessment of glomerular morphological patterns by deep learning algorithms [Research Data]", https://doi.org/10.11588/data/JWZ2CK, heiDATA, V1

Test data and models to the paper "Assessment of glomerular morphological patterns by deep learning algorithms". Different, from other groups, defined CNN-models (saved as .pt-files) are trained to identify nine predefined patterns of glomerular changes. The models are: AlexNet [...

The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]

Aug 24, 2021 - Global Health and Economics

Kohler, Stefan; Ndungwani, Rumbidzai; Burgert, Mark; Sibandze, Dumile; Matse, Sindy; Hettema, Anita, 2021, "The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]", https://doi.org/10.11588/data/KXTQTZ, heiDATA, V1

HIV treatment and prevention as well as other chronic disease care can require regular kidney function assessment based on a creatinine test. To assess the costs of creatinine testing in a public health care system, we conducted activity-based costing during a HIV pre-exposure pr...

Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset]

Jul 27, 2021 - Institute of Pathology Mannheim

Runz, Marlen; Weis, Cleo-Aron, 2021, "Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset]", https://doi.org/10.11588/data/8LKEZF, heiDATA, V1

Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University....

Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data]

Jul 16, 2021 - Division of Infectious Disease and Tropical Medicine

Krüger, Lisa Johanna; Tobian, Frank; Gaeddert, Mary; Lainati, Federica; Klein, Julian A.F.; Schnitzler, Paul; Lindner, Andreas K.; Mockenhaupt, Frank P.; Nikolai, Olga; Seybold, Joachim; Corman, Victor M.; Drosten, Christian; Knorr, Britta; Welker, Andreas; de Vos, Margaretha; Sacks, Jilian A.; Denkinger, Claudia M., 2021, "Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data]", https://doi.org/10.11588/data/D0ACC0, heiDATA, V1

This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab...

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