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1 to 6 of 6 Results
Jun 9, 2015 - Experimental Biophysics
Hausmann, Michael; Müller, Patrick; Hillebrandt, Sabina; Bach, Margund; Kaufmann, Rainer; Zhang, Yang, 2015, "SPDM data capturing radiation induced chromatin conformation changes", https://doi.org/10.11588/data/10031, heiDATA, V3
Using stably transfected HeLa cells expressing either green fluorescent protein (GFP) labelled histone H2B or yellow fluorescent protein (YFP) labelled histone H2A, we investigated the positioning of individual histone proteins in cell nuclei by means of high resolution localizat...
Feb 28, 2022 - Göpfrich Group - Biophysical Engineering of Life
Goepfrich, Kerstin; Walther, Tobias, 2022, "Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]", https://doi.org/10.11588/data/MKOC9S, heiDATA, V1
In the pursuit to produce functioning synthetic cells from the bottom up, DNA nanotechnology has proven to be a powerful tool. However, the crowded yet highly organized arrangement in living cells, bridging from the nano- to the micron-scale, remains challenging to recreate with...
Mar 7, 2022 - Theoretical Physics
Li, Kunhe; Oiwa, Nestor Norio; Cordeiro, Claudette E.; Heermann, Dieter W., 2022, "Prediction and Comparative Analysis of CTCF Binding Sites based on a First Principle Approach [Research Data]", https://doi.org/10.11588/data/RDISCE, heiDATA, V1
The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. T...
Mar 29, 2022 - Theoretical Physics
Li, Kunhe; Oiwa, Nestor N.; Mishra, Sujeet K.; Heermann, Dieter W., 2022, "Inter-Nucleosomal Potentials from Nucleosomal Positioning Data [Research Data]", https://doi.org/10.11588/data/H3KPEU, heiDATA, V1
This dataset accompanies the paper "Inter-Nucleosomal Potentials from Nucleosomal Positioning Data." In this paper, a systematic method to develop inter-nucleosomal potentials between nucleosomes along a chromosome is focused. To this purpose, a modified Lennard-Jones potential i...
Dec 4, 2017 - Experimental Biophysics
Hildenbrand, Georg; Metzler, Philipp; Pilarczyk, Goetz; Bobu, Vladimir; Hosser, Hiltraud; Fleckenstein, Jens; Krufczik, Matthias; Bestvater, Felix; Wenz, Frederik; Hausmann, Michael, 2017, "Dose Enhancement Effects of Gold Nanoparticles Specifically Targeting RNA in Breast Cancer Cells [Dataset]", https://doi.org/10.11588/data/N8NHE2, heiDATA, V1
Localization microscopy has shown to be capable of systematic investigations on the arrangement and counting of cellular uptake of gold nanoparticles (GNP) with nanometer resolution. In this article, we show that the application of specially modified RNA targeting gold nanopartic...
Oct 16, 2014 - Theoretical Physics
Jerabek, Hansjörg; Tark-Dame, Mariliis; Manders, Erik M. M.; Heermann, Dieter W.; van Driel, Roel, 2014, "Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset]", https://doi.org/10.11588/data/10028, heiDATA, V4
Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction.
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