11 to 20 of 54 Results
Kabisch, Maria; Hamann, Ute; Lorenzo Bermejo, Justo, 2018, "Imputation of Missing Genotypes within LD-Blocks Relying on the Basic Coalescent and Beyond [Source Code]", https://doi.org/10.11588/data/X9UEHB, heiDATA, V1
Background Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study... |
Peil, Barbara; Kabisch, Maria; Fischer, Christine; Hamann, Ute; Lorenzo Bermejo, Justo, 2018, "Tailored Selection of Study Individuals to be Sequenced in Order to Improve the Accuracy of Genotype Imputation [Source Code]", https://doi.org/10.11588/data/TT4VM3, heiDATA, V1
The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombi... |
Kesselmeier, Miriam; Lorenzo Bermejo, Justo, 2018, "Robust logistic regression to narrow down the winner's curse for rare and recessive susceptibility variants [Source Code]", https://doi.org/10.11588/data/0Z7H1X, heiDATA, V1
Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unus... |
Oct 11, 2018 - Thematic Research Collection of the Iconography of Venus from the Middle Ages to Modern Times
Bender, K., 2018, "Image Set: Iconography of Venus from the Middle Ages to Modern Times", https://doi.org/10.11588/data/ZPCZ19, heiDATA, V1
The image set is subdivided in nine .zip files according to the first digit of the image id (Ref No in the CSV-files or Ref R in the pdf catalogues) and contains in total 25,682 image files with an average size of 203 kB. The distribution of number of image files is as follows: n... |
Oct 11, 2018 - Thematic Research Collection of the Iconography of Venus from the Middle Ages to Modern Times
Bender, K., 2018, "Artworks of non-European artists", https://doi.org/10.11588/data/LAJUUK, heiDATA, V1
Thematic Research Collection of 1343 artworks (sculptures, reliefs, paintings, frescoes, drawings, prints and illustrations) by non-European artists. |
Höke, Benjamin; Gauß, Florian; Peek, Christina; Stelzner, Jörg, 2018, "Lauchheim II.1. Katalog der Gräber 1–300 [Supplement]", https://doi.org/10.11588/data/SJB7RU, heiDATA, V1
Mit rund 1300 Gräbern aus dem Zeitraum vom späten 5. bis zum späten 6. Jahrhundert ist das Gräberfeld von Lauchheim 'Wasserfurche' (Ostalbkreis) bis heute der größte bekannte merowingerzeitliche Bestattungsplatz Süddeutschlands. In den Jahren 1986 bis 1996 wurde das fast vollstän... |
Oct 5, 2018 - Statistical Genetics
Lorenzo Bermejo, Justo; Boekstegers, Felix; González Silos, Rosa; Marcelain, Katherine; Baez Benavides, Pablo; Barahona Ponce, Carol; Müller, Bettina; Ferreccio, Catterina; Koshiol, Jill; Fischer, Christine; Peil, Barbara; Sinsheimer,Janet; Fuentes Guajardo,Macarena; Barajas, Olga; Gonzalez-Jose, Rolando; Bedoya, Gabriel; Cátira Bortolini, Maria; Canizales-Quinteros,Samuel; Gallo, Carla; Ruiz Linares, Andres; Rothhammer, Francisco, 2018, "Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile [Dataset]", https://doi.org/10.11588/data/IDSI88, heiDATA, V1
Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and disease prevention. Here we investigate possible association... |
Oct 5, 2018
Data publications from the Statistical Genetics Group at Heidelberg University's Institute of Medical Biometry and Informatics. |
Oct 5, 2018 - Statistical Genetics
Hemminki, Kari; Lorenzo Bermejo, Justo, 2018, "Calculation of Population attributable fraction Familial relative risk and Statistical power", https://doi.org/10.11588/data/1KJEDB, heiDATA, V1
Candidate gene studies have become very popular but some of their implicit constraints, such as the familial risk and the population attributable fraction (PAF) conferred by the gene under study, are poorly understood. We model here these parameters for susceptibility genes in te... |
Bender, K., 2018, "The Venus of the Eastern, Southern and Northern European Regions (Catalogue Vol. 6.1)", https://doi.org/10.11588/data/9UXUB0, heiDATA, V1
Topical catalogue of 1371 sculptures, reliefs, paintings, frescoes, drawings, prints and illustrations of 629 identified artists of of the Eastern, Southern and Northern European Regions, from the Middle Ages to Modern Times. 154 pp. With an Index of Artists, a Directory of Owner... |
