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1 to 10 of 14 Results
Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...
Jan 2, 2024 - Data Analysis and Modeling in Medicine (MIISM) - Group Hesser
Jerg, Katharina, 2024, "Real-time definition of single seed placement sensitivity in low-dose-rate prostate brachytherapy [code and patient data]", https://doi.org/10.11588/data/Y3KIPM, heiDATA, V1
PURPOSE: In low-dose-rate brachytherapy iodine seeds are implanted based on a treatment plan, generated with respect to different dose constraints. The quality of the dose distribution depends on a precise seed placement, however, it is not clear which seed misplacements have a l...
Dec 4, 2023 - HITS MBM
Roessner Rita; Michelarakis, Nicholas; Gräter, Frauke; Aponte-Santamaría, Camilo, 2023, "Mechanical forces control the valency of the malaria adhesin VAR2CSA by exposing cryptic glycan binding sites [data]", https://doi.org/10.11588/data/EZHMDU, heiDATA, V1
Plasmodium falciparum (Pf) is responsible for the most lethal form of malaria. VAR2CSA is an adhesin protein expressed by this parasite at the membrane of infected erythrocytes for attachment to the placenta, leading to pregnancy-associated malaria. VAR2CSA is a large 355 kDa mul...
Sep 29, 2023 - Functional Neuroanatomy
Asan, Livia, 2023, "Digital Appendix: Structural cerebrocortical changes in ageing and chronic neuropathic pain - a mouse study correlating magnetic resonance imaging and in vivo two-photon microscopy", https://doi.org/10.11588/data/TPZWAE, heiDATA, V1, UNF:6:E5Th/vUc0jX9a3OPVhNHfQ== [fileUNF]
This is the digital appendix to the dissertation by Livia Asan, titled "Structural cerebrocortical changes in ageing and chronic neuropathic pain - a mouse study correlating magnetic resonance imaging and in vivo two-photon microscopy", at the Faculty of Medicine, Heidelberg, Rup...
May 26, 2023 - Medical Biophysics Group
Ziegler, Katharina; Folkard, Ross; Gonzalez, Antonio; Burghardt, Jan; Antharvedi-Goda, Sailaja; Martín-Cortecero, Jesús; Isaías-Camacho, Emilio; Kaushalya, Sanjeev; Tan, Linette Liqi; Kuner, Thomas; Acuna, Claudio; Kuner, Rohini; Mease, Rebecca; Groh, Alexander, 2023, "Primary Somatosensory Cortex Bidirectionally Modulates Sensory Gain and Nociceptive Behavior in a Layer-Specific Manner [Research Data]", https://doi.org/10.11588/data/D2O0JZ, heiDATA, V2
This dataset contains electrophysiological and behavioral data and codes underlying the figures in Ziegler, K., Folkard, R., Gonzalez, A.J. et al. Primary somatosensory cortex bidirectionally modulates sensory gain and nociceptive behavior in a layer-specific manner. Nat Commun 1...
Jun 17, 2022 - Division of Infectious Disease and Tropical Medicine
Herrmann, Yannis; Lainati, Federica; del Mar Castro, María; Mwamba, Chanda; Kumwenda, Moses; Muyoyeta, Monde; Broger, Tobias; Heinrich, Norbert; Olbrich, Lisa; Corbett, Elizabeth; McMahon, Shannon; Engel, Nora; Denkinger, Claudia, 2022, "User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia [data]", https://doi.org/10.11588/data/PLRQCZ, heiDATA, V1
This data set supports the findings of the FujiLAM qualitative study published in PLOS Global Public Health (Titel:"User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia"). The repository contains our d...
Sep 24, 2021 - AWI Experimental Economics
Vollmann, Martin; Schwieren, Christiane; Mattern, Margarete; Schnell, Knut, 2021, "Let the team fix it? - Performance and mood of depressed workers and coworkers in different work contexts [Research data]", https://doi.org/10.11588/data/PRQILA, heiDATA, V1
Depression in the workplace is a significant factor for reduced personal well-being and productivity. Consequently, this has negative effects on the economic success of the companies in which depressed people are employed. In addition, the economy has to deal with the significant...
Apr 12, 2021 - Institute of Medical Psychology
Warth, Marco, 2021, "Biographical music therapy in palliative care [dataset]", https://doi.org/10.11588/data/Z4XZQ7, heiDATA, V1, UNF:6:Nt/CiJX5oFRkCInlnHZ+Xw== [fileUNF]
1. PURPOSE: Awareness for the importance of psychological and spiritual needs in patients with terminal diseases has increased in recent years. While clinical trials have demonstrated the potential of psychosocial interventions in cancer populations, it remains a challenge to tra...
Feb 11, 2021 - Functional Neuroanatomy
Asan, Livia; Falfán-Melgoza, Claudia; Beretta, Carlo Antonio; Sack, Markus; Zheng, Lei; Weber-Fahr, Wolfgang; Kuner, Thomas; Knabbe, Johannes, 2021, "Cellular correlates of gray matter volume changes in magnetic resonance morphometry identified by two-photon microscopy [Dataset]", https://doi.org/10.11588/data/04HPWW, heiDATA, V1, UNF:6:t1jhJE4myjockvvIVpnP7A== [fileUNF]
This dataset accompanies the article of the same title in the journal Scientific Reports. It includes a) spreadsheets of data values for each plot in the main figures, b) all raw image data from Two-Photon in vivo microscopy (2pii) c) Custom code d) representative subsets of segm...
Apr 6, 2020 - Anders Group
Roider, Tobias; Seufert, Julian; Uvarovskii, Alexey; Frauhammer, Felix; Bordas, Marie; Abedpour, Nima; Stolarczyk, Marta; Mallm, Jan-Philipp; Herbst, Sophie A.; Bruch, Peter-Martin; Balke-Want, Hyatt; Hundemer, Michael; Rippe, Karsten; Goeppert, Benjamin; Seiffert, Martina; Brors, Benedikt; Mechtersheimer, Gunhild; Zenz, Thorsten; Peifer, Martin; Chapuy, Björn; Schlesner, Matthias; Müller-Tidow, Carsten; Fröhling, Stefan; Huber, Wolfgang; Anders, Simon; Sascha Dietrich, 2020, "Dissecting intratumor heterogeneity of nodal B cell lymphomas at transcriptional, genetic, and drug response levels", https://doi.org/10.11588/data/VRJUNV, heiDATA, V1, UNF:6:AlKw3YwYZ82Ty5CxnC4D5w== [fileUNF]
Tumour heterogeneity encompasses both the malignant cells and their microenvironment. While heterogeneity between individual patients is known to affect the efficacy of cancer therapy, most personalized treatment approaches do not account for intratumor heterogeneity. We addresse...
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