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Subject: Medicine, Health and Life Sciences

41 to 50 of 157 Results

Monosynaptic trans-collicular pathways link mouse whisker circuits to integrate somatosensory and motor cortical signals [Research Data] Mar 27, 2023 - Medical Biophysics Group Martín-Cortecero, Jesús; Isaías-Camacho, Emilio Ulises; Boztepe, Berin; Ziegler, Katharina; Mease, Rebecca Audrey; Groh, Alexander, 2023, "Monosynaptic trans-collicular pathways link mouse whisker circuits to integrate somatosensory and motor cortical signals [Research Data]", https://doi.org/10.11588/data/DNOSZG, heiDATA, V2 This dataset contains electrophysiological spike time data and figure data for anatomical quantifications reported in Martín-Cortecero et al. Monosynaptic trans-collicular pathways for sensory-motor integration in the whisker system (2023). https://doi.org/10.1371/journal.pbio.30...
Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data] Mar 24, 2023 - HITS MBM Rennekamp, Benedikt; Gräter, Frauke, 2023, "Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data]", https://doi.org/10.11588/data/HJ6SVM, heiDATA, V1, UNF:6:Da6omTKjrSvNcDwyJxuHOg== [fileUNF] This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related pu...
Medical Biophysics Group (Heidelberg University, Medical Faculty Heidelberg) Mar 13, 2023 Open Research Data from Medical Biophysics Group of Prof. Alexander Groh at the Medical Faculty Heidelberg.
Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections [data] Mar 2, 2023 - AG Computational Diagnostic Kriegsmann, Katharina; Lobers, Fritjof; Zgorzelski, Christiane; Kriegsmann, Jörg; Meliß, Rolf Rüdiger; Sack, Ulrich; Steinbuss,Georg; Kriegsmann,Mark, 2023, "Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections [data]", https://doi.org/10.11588/data/7QCR8S, heiDATA, V1 Basal cell carcinoma (BCC), squamous cell carcinoma (SqCC) and melanoma are among the most common cancer types. Correct diagnosis based on histological evaluation after biopsy or excision is paramount for adequate therapy stratification. Deep learning on histological slides has b...
AG Computational Diagnostic(Center of Internal Medicine, Heidelberg University Hospital) Mar 1, 2023 Research data that helps improving diagnostics via algorithms.
Prefrontal engrams of long-term fear memory and pain Feb 23, 2023 - Heidelberg Pain Consortium - SFB 1158 Oswald, Manfred Josef; Beretta, Carlo Antonio; Stegemann, Alina; Han, Yechao; Kuner, Rohini, 2023, "Prefrontal engrams of long-term fear memory and pain", https://doi.org/10.11588/data/VEEIDP, heiDATA, V1, UNF:6:QT9272Lmh0bGgVxcezQ+yw== [fileUNF] This dataset contains electrophysiological spike time data and associated analysis procedures as well as image analysis scripts reported in Stegemann et al. Prefrontal engrams of long-term fear memory perpetuate pain perception. Nature Neuroscience (2023). Abstract: A painful epi...
Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes Feb 20, 2023 - Stoecklin_BCH_MI3 Reitter, Sonja; Schoelz, Christian; Stoecklin, Georg, 2023, "Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes", https://doi.org/10.11588/data/M5ZUPP, heiDATA, V1 While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of riboso...
Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data] Feb 15, 2023 - HITS MBM Buhr, Jannik; Franz, Florian; Gräter, Frauke, 2023, "Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data]", https://doi.org/10.11588/data/BQTQUN, heiDATA, V1 Focal adhesions (FAs) mediate the interaction of the cytoskeleton with the extracellular matrix (ECM) in a highly dynamic fashion. talin is a central regulator, adaptor protein and mechano-sensor of focal adhesion complexes. For recruitment and firm attachment at FAs, talin’s N-t...
Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis] Feb 6, 2023 - Forschungsgruppe AG Nikendei Nowak, Jonathan; Rollmann, Ivo; Kindermann, David; Nikendei, Christoph, 2023, "Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis]", https://doi.org/10.11588/data/W63LJJ, heiDATA, V1 This dataset contains the code for the analysis in R which was used to calculate the results for the study 'Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sam...
Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data] Jan 17, 2023 - NCT - Section of Translational Medical Ethics Köngeter, Anja; Schickhardt, Christoph; Jungkunz, Martin; Mehlis, Katja; Winkler, Eva C., 2022, "Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data]", https://doi.org/10.11588/data/5JCEVW, heiDATA, V2, UNF:6:rCJxTnlT0ZCX6/Tn/Zv78g== [fileUNF] This is the research data from the publication "Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey." The research data includes the questionnaire, the data set used, and a description of the data preparat...

Monosynaptic trans-collicular pathways link mouse whisker circuits to integrate somatosensory and motor cortical signals [Research Data]

Mar 27, 2023 - Medical Biophysics Group

Martín-Cortecero, Jesús; Isaías-Camacho, Emilio Ulises; Boztepe, Berin; Ziegler, Katharina; Mease, Rebecca Audrey; Groh, Alexander, 2023, "Monosynaptic trans-collicular pathways link mouse whisker circuits to integrate somatosensory and motor cortical signals [Research Data]", https://doi.org/10.11588/data/DNOSZG, heiDATA, V2

This dataset contains electrophysiological spike time data and figure data for anatomical quantifications reported in Martín-Cortecero et al. Monosynaptic trans-collicular pathways for sensory-motor integration in the whisker system (2023). https://doi.org/10.1371/journal.pbio.30...

Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data]

Mar 24, 2023 - HITS MBM

Rennekamp, Benedikt; Gräter, Frauke, 2023, "Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data]", https://doi.org/10.11588/data/HJ6SVM, heiDATA, V1, UNF:6:Da6omTKjrSvNcDwyJxuHOg== [fileUNF]

This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related pu...

Medical Biophysics Group (Heidelberg University, Medical Faculty Heidelberg)

Mar 13, 2023

Open Research Data from Medical Biophysics Group of Prof. Alexander Groh at the Medical Faculty Heidelberg.

Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections [data]

Mar 2, 2023 - AG Computational Diagnostic

Kriegsmann, Katharina; Lobers, Fritjof; Zgorzelski, Christiane; Kriegsmann, Jörg; Meliß, Rolf Rüdiger; Sack, Ulrich; Steinbuss,Georg; Kriegsmann,Mark, 2023, "Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections [data]", https://doi.org/10.11588/data/7QCR8S, heiDATA, V1

Basal cell carcinoma (BCC), squamous cell carcinoma (SqCC) and melanoma are among the most common cancer types. Correct diagnosis based on histological evaluation after biopsy or excision is paramount for adequate therapy stratification. Deep learning on histological slides has b...

AG Computational Diagnostic(Center of Internal Medicine, Heidelberg University Hospital)

Mar 1, 2023

Research data that helps improving diagnostics via algorithms.

Prefrontal engrams of long-term fear memory and pain

Feb 23, 2023 - Heidelberg Pain Consortium - SFB 1158

Oswald, Manfred Josef; Beretta, Carlo Antonio; Stegemann, Alina; Han, Yechao; Kuner, Rohini, 2023, "Prefrontal engrams of long-term fear memory and pain", https://doi.org/10.11588/data/VEEIDP, heiDATA, V1, UNF:6:QT9272Lmh0bGgVxcezQ+yw== [fileUNF]

This dataset contains electrophysiological spike time data and associated analysis procedures as well as image analysis scripts reported in Stegemann et al. Prefrontal engrams of long-term fear memory perpetuate pain perception. Nature Neuroscience (2023). Abstract: A painful epi...

Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes

Feb 20, 2023 - Stoecklin_BCH_MI3

Reitter, Sonja; Schoelz, Christian; Stoecklin, Georg, 2023, "Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes", https://doi.org/10.11588/data/M5ZUPP, heiDATA, V1

While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of riboso...

Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data]

Feb 15, 2023 - HITS MBM

Buhr, Jannik; Franz, Florian; Gräter, Frauke, 2023, "Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data]", https://doi.org/10.11588/data/BQTQUN, heiDATA, V1

Focal adhesions (FAs) mediate the interaction of the cytoskeleton with the extracellular matrix (ECM) in a highly dynamic fashion. talin is a central regulator, adaptor protein and mechano-sensor of focal adhesion complexes. For recruitment and firm attachment at FAs, talin’s N-t...

Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis]

Feb 6, 2023 - Forschungsgruppe AG Nikendei

Nowak, Jonathan; Rollmann, Ivo; Kindermann, David; Nikendei, Christoph, 2023, "Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis]", https://doi.org/10.11588/data/W63LJJ, heiDATA, V1

This dataset contains the code for the analysis in R which was used to calculate the results for the study 'Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sam...

Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data]

Jan 17, 2023 - NCT - Section of Translational Medical Ethics

Köngeter, Anja; Schickhardt, Christoph; Jungkunz, Martin; Mehlis, Katja; Winkler, Eva C., 2022, "Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data]", https://doi.org/10.11588/data/5JCEVW, heiDATA, V2, UNF:6:rCJxTnlT0ZCX6/Tn/Zv78g== [fileUNF]

This is the research data from the publication "Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey." The research data includes the questionnaire, the data set used, and a description of the data preparat...

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