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1 to 10 of 14 Results
Jun 17, 2022 - Division of Infectious Disease and Tropical Medicine
Herrmann, Yannis; Lainati, Federica; del Mar Castro, María; Mwamba, Chanda; Kumwenda, Moses; Muyoyeta, Monde; Broger, Tobias; Heinrich, Norbert; Olbrich, Lisa; Corbett, Elizabeth; McMahon, Shannon; Engel, Nora; Denkinger, Claudia, 2022, "User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia [data]", https://doi.org/10.11588/data/PLRQCZ, heiDATA, V1
This data set supports the findings of the FujiLAM qualitative study published in PLOS Global Public Health (Titel:"User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia"). The repository contains our d...
Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...
Jun 9, 2015 - Experimental Biophysics
Hausmann, Michael; Müller, Patrick; Hillebrandt, Sabina; Bach, Margund; Kaufmann, Rainer; Zhang, Yang, 2015, "SPDM data capturing radiation induced chromatin conformation changes", https://doi.org/10.11588/data/10031, heiDATA, V3
Using stably transfected HeLa cells expressing either green fluorescent protein (GFP) labelled histone H2B or yellow fluorescent protein (YFP) labelled histone H2A, we investigated the positioning of individual histone proteins in cell nuclei by means of high resolution localizat...
Jan 2, 2024 - Data Analysis and Modeling in Medicine (MIISM) - Group Hesser
Jerg, Katharina, 2024, "Real-time definition of single seed placement sensitivity in low-dose-rate prostate brachytherapy [code and patient data]", https://doi.org/10.11588/data/Y3KIPM, heiDATA, V1
PURPOSE: In low-dose-rate brachytherapy iodine seeds are implanted based on a treatment plan, generated with respect to different dose constraints. The quality of the dose distribution depends on a precise seed placement, however, it is not clear which seed misplacements have a l...
May 26, 2023 - Medical Biophysics Group
Ziegler, Katharina; Folkard, Ross; Gonzalez, Antonio; Burghardt, Jan; Antharvedi-Goda, Sailaja; Martín-Cortecero, Jesús; Isaías-Camacho, Emilio; Kaushalya, Sanjeev; Tan, Linette Liqi; Kuner, Thomas; Acuna, Claudio; Kuner, Rohini; Mease, Rebecca; Groh, Alexander, 2023, "Primary Somatosensory Cortex Bidirectionally Modulates Sensory Gain and Nociceptive Behavior in a Layer-Specific Manner [Research Data]", https://doi.org/10.11588/data/D2O0JZ, heiDATA, V2
This dataset contains electrophysiological and behavioral data and codes underlying the figures in Ziegler, K., Folkard, R., Gonzalez, A.J. et al. Primary somatosensory cortex bidirectionally modulates sensory gain and nociceptive behavior in a layer-specific manner. Nat Commun 1...
Nov 27, 2018 - Diagnostic and Interventional Radiology
Triphan, Simon, 2018, "Perfusion quantification data for "Towards Quantitative Perfusion MRI of the Lung in COPD: The Problem of Short-Term Repeatability"", https://doi.org/10.11588/data/ZPEZPX, heiDATA, V1, UNF:6:SE0iKbhWdsMOrcUkd706AA== [fileUNF]
ABSTRACT Purpose 4D perfusion magnetic resonance imaging (MRI) with intravenous injection of contrast agent allows for a radiation-free assessment of regional lung function. It is therefore a valuable method to monitor response to treatment in patients with chronic obstructive pu...
Dec 4, 2023 - HITS MBM
Roessner Rita; Michelarakis, Nicholas; Gräter, Frauke; Aponte-Santamaría, Camilo, 2023, "Mechanical forces control the valency of the malaria adhesin VAR2CSA by exposing cryptic glycan binding sites [data]", https://doi.org/10.11588/data/EZHMDU, heiDATA, V1
Plasmodium falciparum (Pf) is responsible for the most lethal form of malaria. VAR2CSA is an adhesin protein expressed by this parasite at the membrane of infected erythrocytes for attachment to the placenta, leading to pregnancy-associated malaria. VAR2CSA is a large 355 kDa mul...
Sep 24, 2021 - AWI Experimental Economics
Vollmann, Martin; Schwieren, Christiane; Mattern, Margarete; Schnell, Knut, 2021, "Let the team fix it? - Performance and mood of depressed workers and coworkers in different work contexts [Research data]", https://doi.org/10.11588/data/PRQILA, heiDATA, V1
Depression in the workplace is a significant factor for reduced personal well-being and productivity. Consequently, this has negative effects on the economic success of the companies in which depressed people are employed. In addition, the economy has to deal with the significant...
May 18, 2018 - Institute of Pathology Mannheim
Cleo-Aron Weis, 2018, "Histopathology of thymectomy specimens from the MGTX-trial", https://doi.org/10.11588/data/NWE2JJ, heiDATA, V1, UNF:6:Od2UlnHG3ctanb4ikzIx4g== [fileUNF]
Background: The thymectomy specimens from the “thymectomy trial in non-thymomatous myasthenia gravis patients receiving prednisone therapy” (MGTX) [1] underwent rigid and comprehensive work-up, which results in a unique, spatially mapped dataset. Fig. 1 Specimen work-up: Work-up...
Apr 6, 2020 - Anders Group
Roider, Tobias; Seufert, Julian; Uvarovskii, Alexey; Frauhammer, Felix; Bordas, Marie; Abedpour, Nima; Stolarczyk, Marta; Mallm, Jan-Philipp; Herbst, Sophie A.; Bruch, Peter-Martin; Balke-Want, Hyatt; Hundemer, Michael; Rippe, Karsten; Goeppert, Benjamin; Seiffert, Martina; Brors, Benedikt; Mechtersheimer, Gunhild; Zenz, Thorsten; Peifer, Martin; Chapuy, Björn; Schlesner, Matthias; Müller-Tidow, Carsten; Fröhling, Stefan; Huber, Wolfgang; Anders, Simon; Sascha Dietrich, 2020, "Dissecting intratumor heterogeneity of nodal B cell lymphomas at transcriptional, genetic, and drug response levels", https://doi.org/10.11588/data/VRJUNV, heiDATA, V1, UNF:6:AlKw3YwYZ82Ty5CxnC4D5w== [fileUNF]
Tumour heterogeneity encompasses both the malignant cells and their microenvironment. While heterogeneity between individual patients is known to affect the efficacy of cancer therapy, most personalized treatment approaches do not account for intratumor heterogeneity. We addresse...
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