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Subject: Medicine, Health and Life Sciences

51 to 60 of 163 Results

AG Computational Diagnostic(Center of Internal Medicine, Heidelberg University Hospital) Mar 1, 2023 Research data that helps improving diagnostics via algorithms.
Prefrontal engrams of long-term fear memory and pain Feb 23, 2023 - Heidelberg Pain Consortium - SFB 1158 Oswald, Manfred Josef; Beretta, Carlo Antonio; Stegemann, Alina; Han, Yechao; Kuner, Rohini, 2023, "Prefrontal engrams of long-term fear memory and pain", https://doi.org/10.11588/data/VEEIDP, heiDATA, V1, UNF:6:QT9272Lmh0bGgVxcezQ+yw== [fileUNF] This dataset contains electrophysiological spike time data and associated analysis procedures as well as image analysis scripts reported in Stegemann et al. Prefrontal engrams of long-term fear memory perpetuate pain perception. Nature Neuroscience (2023). Abstract: A painful epi...
Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes Feb 20, 2023 - Stoecklin_BCH_MI3 Reitter, Sonja; Schoelz, Christian; Stoecklin, Georg, 2023, "Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes", https://doi.org/10.11588/data/M5ZUPP, heiDATA, V1 While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of riboso...
Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data] Feb 15, 2023 - HITS MBM Buhr, Jannik; Franz, Florian; Gräter, Frauke, 2023, "Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data]", https://doi.org/10.11588/data/BQTQUN, heiDATA, V1 Focal adhesions (FAs) mediate the interaction of the cytoskeleton with the extracellular matrix (ECM) in a highly dynamic fashion. talin is a central regulator, adaptor protein and mechano-sensor of focal adhesion complexes. For recruitment and firm attachment at FAs, talin’s N-t...
Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis] Feb 6, 2023 - Forschungsgruppe AG Nikendei Nowak, Jonathan; Rollmann, Ivo; Kindermann, David; Nikendei, Christoph, 2023, "Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis]", https://doi.org/10.11588/data/W63LJJ, heiDATA, V1 This dataset contains the code for the analysis in R which was used to calculate the results for the study 'Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sam...
Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data] Jan 17, 2023 - NCT - Section of Translational Medical Ethics Köngeter, Anja; Schickhardt, Christoph; Jungkunz, Martin; Mehlis, Katja; Winkler, Eva C., 2022, "Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data]", https://doi.org/10.11588/data/5JCEVW, heiDATA, V2, UNF:6:rCJxTnlT0ZCX6/Tn/Zv78g== [fileUNF] This is the research data from the publication "Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey." The research data includes the questionnaire, the data set used, and a description of the data preparat...
NLU anonymized(Heidelberg University) Nov 24, 2022 to be added
HITS MBM(Heidelberg Institute for Theoretical Studies) Nov 8, 2022 Data publications from the the Molecular Biomechanics (MBM) group at HITS. Shareholders of HITS are the “HITS-Stiftung”, Heidelberg University and the Karlsruhe Institute of Technology (KIT)
Activity of AcD and nonAcD cells during high-frequency network oscillations [data] Sep 22, 2022 - Bothlab Hodapp, Alexander; Kaiser, Martin E.; Thome, Christian; Ding, Lingjun; Rozov, Andrei; Klumpp, Matthias; Stevens, Nikolas; Stingl, Moritz; Sackmann, Tina; Lehmann, Nadja; Draguhn, Andreas; Burgalossi, Andrea; Engelhardt, Maren; Both, Martin, 2022, "Activity of AcD and nonAcD cells during high-frequency network oscillations [data]", https://doi.org/10.11588/data/JWLFFZ, heiDATA, V1, UNF:6:IbIOEy1OPRgP05Qd2QIN4w== [fileUNF] Information processing in neuronal networks involves the recruitment of selected neurons into coordinated spatiotemporal activity patterns. This sparse activation results from widespread synaptic inhibition in conjunction with neuron-specific synaptic excitation. We report the se...
Bothlab(Institute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University) Sep 22, 2022 The research group focuses on the rodent hippocampus as a model system. This cortical region is centrally involved in declarative memory processes and shows pronounced and distinct patterns of network activity (e.g. gamma oscillations, sharp wave-ripples): Additionally, hippocamp...

AG Computational Diagnostic(Center of Internal Medicine, Heidelberg University Hospital)

Mar 1, 2023

Research data that helps improving diagnostics via algorithms.

Prefrontal engrams of long-term fear memory and pain

Feb 23, 2023 - Heidelberg Pain Consortium - SFB 1158

Oswald, Manfred Josef; Beretta, Carlo Antonio; Stegemann, Alina; Han, Yechao; Kuner, Rohini, 2023, "Prefrontal engrams of long-term fear memory and pain", https://doi.org/10.11588/data/VEEIDP, heiDATA, V1, UNF:6:QT9272Lmh0bGgVxcezQ+yw== [fileUNF]

This dataset contains electrophysiological spike time data and associated analysis procedures as well as image analysis scripts reported in Stegemann et al. Prefrontal engrams of long-term fear memory perpetuate pain perception. Nature Neuroscience (2023). Abstract: A painful epi...

Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes

Feb 20, 2023 - Stoecklin_BCH_MI3

Reitter, Sonja; Schoelz, Christian; Stoecklin, Georg, 2023, "Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes", https://doi.org/10.11588/data/M5ZUPP, heiDATA, V1

While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of riboso...

Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data]

Feb 15, 2023 - HITS MBM

Buhr, Jannik; Franz, Florian; Gräter, Frauke, 2023, "Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data]", https://doi.org/10.11588/data/BQTQUN, heiDATA, V1

Focal adhesions (FAs) mediate the interaction of the cytoskeleton with the extracellular matrix (ECM) in a highly dynamic fashion. talin is a central regulator, adaptor protein and mechano-sensor of focal adhesion complexes. For recruitment and firm attachment at FAs, talin’s N-t...

Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis]

Feb 6, 2023 - Forschungsgruppe AG Nikendei

Nowak, Jonathan; Rollmann, Ivo; Kindermann, David; Nikendei, Christoph, 2023, "Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis]", https://doi.org/10.11588/data/W63LJJ, heiDATA, V1

This dataset contains the code for the analysis in R which was used to calculate the results for the study 'Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sam...

Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data]

Jan 17, 2023 - NCT - Section of Translational Medical Ethics

Köngeter, Anja; Schickhardt, Christoph; Jungkunz, Martin; Mehlis, Katja; Winkler, Eva C., 2022, "Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data]", https://doi.org/10.11588/data/5JCEVW, heiDATA, V2, UNF:6:rCJxTnlT0ZCX6/Tn/Zv78g== [fileUNF]

This is the research data from the publication "Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey." The research data includes the questionnaire, the data set used, and a description of the data preparat...

NLU anonymized(Heidelberg University)

Nov 24, 2022

to be added

HITS MBM(Heidelberg Institute for Theoretical Studies)

Nov 8, 2022

Data publications from the the Molecular Biomechanics (MBM) group at HITS. Shareholders of HITS are the “HITS-Stiftung”, Heidelberg University and the Karlsruhe Institute of Technology (KIT)

Activity of AcD and nonAcD cells during high-frequency network oscillations [data]

Sep 22, 2022 - Bothlab

Hodapp, Alexander; Kaiser, Martin E.; Thome, Christian; Ding, Lingjun; Rozov, Andrei; Klumpp, Matthias; Stevens, Nikolas; Stingl, Moritz; Sackmann, Tina; Lehmann, Nadja; Draguhn, Andreas; Burgalossi, Andrea; Engelhardt, Maren; Both, Martin, 2022, "Activity of AcD and nonAcD cells during high-frequency network oscillations [data]", https://doi.org/10.11588/data/JWLFFZ, heiDATA, V1, UNF:6:IbIOEy1OPRgP05Qd2QIN4w== [fileUNF]

Information processing in neuronal networks involves the recruitment of selected neurons into coordinated spatiotemporal activity patterns. This sparse activation results from widespread synaptic inhibition in conjunction with neuron-specific synaptic excitation. We report the se...

Bothlab(Institute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University)

Sep 22, 2022

The research group focuses on the rodent hippocampus as a model system. This cortical region is centrally involved in declarative memory processes and shows pronounced and distinct patterns of network activity (e.g. gamma oscillations, sharp wave-ripples): Additionally, hippocamp...

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