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1 to 10 of 14 Results
Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...
Apr 18, 2024 - Global Health and Economics
Kohler, Stefan; Sitali, Norman; Achar, Jay; Paul, Nicolas, 2024, "The contribution of drug import to the cost of tuberculosis treatment: a cost analysis of longer, shorter and short drug regimens for Karakalpakstan, Uzbekistan [Research Data]", https://doi.org/10.11588/data/LTTWSQ, heiDATA, V1
Tuberculosis (TB) programs depend on a continuous supply of large amounts of high-quality TB drugs. When TB programs procure TB drugs from international suppliers, such as the Global Drug Facility, they can incur import costs for international transport, customs clearance, and na...
Feb 25, 2024 - Integrative Virology
Ananth, Swetha, 2024, "Spatial resolution of HIV-1 post-entry steps in resting CD4 T cells [data]", https://doi.org/10.11588/data/MUXYRY, heiDATA, V1
#enter description, e.g. paper abstract
Jan 2, 2024 - Data Analysis and Modeling in Medicine (MIISM) - Group Hesser
Jerg, Katharina, 2024, "Real-time definition of single seed placement sensitivity in low-dose-rate prostate brachytherapy [code and patient data]", https://doi.org/10.11588/data/Y3KIPM, heiDATA, V1
PURPOSE: In low-dose-rate brachytherapy iodine seeds are implanted based on a treatment plan, generated with respect to different dose constraints. The quality of the dose distribution depends on a precise seed placement, however, it is not clear which seed misplacements have a l...
Apr 18, 2024 - Global Health and Economics
Kohler, Stefan; Sitali, Norman; Achar, Jay; Paul, Nicolas, 2024, "Programme costs of longer and shorter tuberculosis drug regimens and drug import: a modelling study for Karakalpakstan, Uzbekistan [Research Data]", https://doi.org/10.11588/data/2NZSXC, heiDATA, V1, UNF:6:XNSx0CjhN0IIi/rvvB01gQ== [fileUNF]
Background: The introduction of new and often shorter tuberculosis (TB) drug regimens affects the cost of TB programmes. Methods: We modelled drug purchase and import costs for 20-month, 9-month and 4- to 6-month TB drug regimens based on 2016–2020 treatment numbers from a TB pro...
Mar 4, 2024 - Forschungsgruppe AG Nikendei
Rollmann, Ivo; Kindermann, David; Stahl-Toyota, Sophia; Nowak, Jonathan; Orth, Maximilian; Friederich, Hans-Christoph; Nikendei, Christoph, 2024, "Prediction of improvement in Personality Functioning. Utilisation of machine learning to filter relevant variables for prediction [dataset]", https://doi.org/10.11588/data/50WFVL, heiDATA, V1, UNF:6:B4RPojcFDrMxlhi/kXeKpQ== [fileUNF]
Introduction. Since its introduction in the DSM-5 and the ICD-11, the construct of personality functioning has received increased research interest. Recent studies have shown that psychotherapy contributes to an improvement in personality functioning. However, it remains unclear...
Apr 18, 2024 - Global Health and Economics
Kohler, Stefan; Dalal, Shona; Hettema, Anita; Matse, Sindy; Bärnighausen, Till; Paul, Nicolas, 2024, "Out-of-pocket Expenses and Time Spent on Clinic Visits Among HIV Pre-exposure Prophylaxis Users and Other Clinic Attendees in Eswatini", https://doi.org/10.11588/data/OYUCUZ, heiDATA, V1, UNF:6:fCKr9iVPE677CM/2iOnvPA== [fileUNF]
User costs constitute a barrier to the uptake of HIV pre-exposure prophylaxis (PrEP), but their magnitude appears rarely assessed. In this prospective observational study, we assessed self-reported out-of-pocket expenses (OOPE) and time spent on clinic visits during a PrEP demons...
Jan 26, 2024 - Siemens Lab
Marty-Lombardi, Sebastián; Lu, Shiying; Ambroziak, Wojciech; Schrenk-Siemens, Katrin; Wang, Jialin; DePaoli-Roach, Anna A.; Hagenston, Anna M.; Wende, Hagen; Tappe-Theodor, Anke; Simonetti, Manuela; Bading, Hilmar; Okun, Jürgen G.; Kuner, Rohini; Fleming, Thomas; Siemens, Jan, 2024, "Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain [data]", https://doi.org/10.11588/data/AMDH7G, heiDATA, V1
Long-lasting pain stimuli can trigger maladaptive changes in the spinal cord, reminiscent of plasticity associated with memory formation. Metabolic coupling between astrocytes and neurons has been implicated in neuronal plasticity and memory formation in the CNS, but neither its...
Apr 18, 2024 - Global Health and Economics
Kohler, Stefan; Dalal, Shona; Hettema, Anita; Matse, Sindy; Bärnighausen, Till; Paul, Nicolas, 2024, "Human resource needs and costs for nurse-led HIV pre-exposure prophylaxis provision in primary care in Eswatini and opportunities for task sharing [Research Data]", https://doi.org/10.11588/data/JABBCS, heiDATA, V1, UNF:6:N6VH0ThbWDXXKVXB2DSKPw== [fileUNF]
Background: The global expansion of HIV pre-exposure prophylaxis (PrEP) includes health systems that face a shortage of skilled health care workers (HCWs). We estimated the human resource needs and costs for providing PrEP in nurse-led primary care clinics in Eswatini. Furthermor...
Apr 18, 2024 - Global Health and Economics
Kohler, Stefan; Bärnighausen, Till; Eichenauer, Jutta; Scheichenbauer, Christel; Paul, Nicolas, 2024, "Gesundheit und berufliche Zufriedenheit von freiberuflichen und angestellten Hebammen: Ergebnisse einer Hebammenbefragung in Baden-Württemberg [Forschungsdaten]", https://doi.org/10.11588/data/AESW63, heiDATA, V1, UNF:6:ry6jPOc6QEiV1shLoJuJ/g== [fileUNF]
Hintergrund: Seit einigen Jahren wird in Deutschland vielerorts ein Mangel an Hebammen diskutiert. In dieser Studie befragten wir freiberufliche und angestellte Hebammen in Baden-Württemberg zu ihrer Gesundheit sowie beruflichen Zufriedenheit. Methode In Zusammenarbeit: mit dem H...
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