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1 to 10 of 157 Results
ACSeg: Automated 3D Cytoplasm Segmentation in Soft X-Ray Tomography [Jurkat T cell data]
Mar 21, 2024 - AG Weinhardt
Erozan, Ayse; Heuveline, Vincent; Weinhardt, Venera, 2024, "ACSeg: Automated 3D Cytoplasm Segmentation in Soft X-Ray Tomography [Jurkat T cell data]", https://doi.org/10.11588/data/XEBZLL, heiDATA, V1
The structure of cells is a key to understanding cellular function, diagnosing diseases, and developing new treatments. Soft X-ray tomography is uniquely used to access 3D cellular structure of various cells at statistically significant sample sizes. These datasets are reconstruc...
AG Weinhardt(Heidelberg University, Centre of Organismic Studies )
Mar 21, 2024
Evaluation of Bioprinted Autologous Cartilage Grafts in an Immunocompetent Rabbit Model [data]
Mar 11, 2024 - Otorhinolaryngology, Head and Neck Surgery
Gvaramia, David; Fisch, Philipp; Flégeau, Killian; Huber, Lena; Kern, Johann; Jakob, Yvonne; Hirsch, Daniela; Rotter, Nicole, 2024, "Evaluation of Bioprinted Autologous Cartilage Grafts in an Immunocompetent Rabbit Model [data]", https://doi.org/10.11588/data/0BQTPT, heiDATA, V1
The current gold standard of auricular reconstruction involves a highly time-consuming manual graft assembly from autologous costal cartilage. The intervention may require multiple surgical procedures and lead to donor-site morbidity, while the outcome is highly dependent on indi...
Otorhinolaryngology, Head and Neck Surgery(Heidelberg University)
Mar 11, 2024
Prediction of improvement in Personality Functioning. Utilisation of machine learning to filter relevant variables for prediction [dataset]
Mar 4, 2024 - Forschungsgruppe AG Nikendei
Rollmann, Ivo; Kindermann, David; Stahl-Toyota, Sophia; Nowak, Jonathan; Orth, Maximilian; Friederich, Hans-Christoph; Nikendei, Christoph, 2024, "Prediction of improvement in Personality Functioning. Utilisation of machine learning to filter relevant variables for prediction [dataset]", https://doi.org/10.11588/data/50WFVL, heiDATA, V1, UNF:6:B4RPojcFDrMxlhi/kXeKpQ== [fileUNF]
Introduction. Since its introduction in the DSM-5 and the ICD-11, the construct of personality functioning has received increased research interest. Recent studies have shown that psychotherapy contributes to an improvement in personality functioning. However, it remains unclear...
Characterization of Cognitive Functioning in Complex PTSD compared to Non-Complex PTSD [data]
Feb 29, 2024 - Forschungsgruppe AG Nikendei
Martin, Zoe-Sofia; Terhoeven, Valentin; Jaehn, Anna; Roesch-Ely, Daniela; Friederich, Hans-Christoph; Nikendei, Christoph; Kindermann, David, 2024, "Characterization of Cognitive Functioning in Complex PTSD compared to Non-Complex PTSD [data]", https://doi.org/10.11588/data/B3HNSQ, heiDATA, V1, UNF:6:tiV8SCpFx9qR8s7sZKn5vA== [fileUNF]
The aim of the study is to enhance understanding of cognitive functioning and its predictors in cPTSD compared with non-complex PTSD (ncPTSD).
Spatial resolution of HIV-1 post-entry steps in resting CD4 T cells [data]
Spatial resolution of HIV-1 post-entry steps in resting CD4 T cells [data]
Feb 25, 2024 - Integrative Virology
Ananth, Swetha, 2024, "Spatial resolution of HIV-1 post-entry steps in resting CD4 T cells [data]", https://doi.org/10.11588/data/MUXYRY, heiDATA, V1
#enter description, e.g. paper abstract
Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]
Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]
Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...
Siemens Lab(Heidelberg University, Institute of Pharmacology)
Feb 12, 2024
Open Research Data from the Siemens Lab at the Institute of Pharmacology of Heidelberg University.
Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain [data]
Jan 26, 2024 - Siemens Lab
Marty-Lombardi, Sebastián; Lu, Shiying; Ambroziak, Wojciech; Schrenk-Siemens, Katrin; Wang, Jialin; DePaoli-Roach, Anna A.; Hagenston, Anna M.; Wende, Hagen; Tappe-Theodor, Anke; Simonetti, Manuela; Bading, Hilmar; Okun, Jürgen G.; Kuner, Rohini; Fleming, Thomas; Siemens, Jan, 2024, "Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain [data]", https://doi.org/10.11588/data/AMDH7G, heiDATA, V1
Long-lasting pain stimuli can trigger maladaptive changes in the spinal cord, reminiscent of plasticity associated with memory formation. Metabolic coupling between astrocytes and neurons has been implicated in neuronal plasticity and memory formation in the CNS, but neither its...
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