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1 to 10 of 27 Results

Developmental origins and evolution of pallial cell types and structures in birds - Data Apr 30, 2024 - Kaessmann Lab Zaremba, Bastienne; Fallahshahroudi, Amir; Schneider, Céline; Schmidt, Julia; Sarropoulos, Ioannis; Leushkin, Evgeny; Berki, Bianka; Van Poucke, Enya; Jensen, Per; Senovilla-Ganzo, Rodrigo; Hervas-Sotomayor, Francisca; Trost, Nils; Lamanna, Francesco; Sepp, Mari; García-Moreno, Fernando; Kaessmann, Henrik, 2024, "Developmental origins and evolution of pallial cell types and structures in birds - Data", https://doi.org/10.11588/data/BX6REK, heiDATA, V1, UNF:6:4DNo7hOUtj/vCfSrVp37wA== [fileUNF] The advanced cognitive abilities of birds rival those of mammals and have been attributed to evolutionary innovations in the pallium. However, a comprehensive cellular characterization of this brain region in birds has been lacking. We scrutinized the structures, cell types and e...
Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data] Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF] Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...
Real-time definition of single seed placement sensitivity in low-dose-rate prostate brachytherapy [code and patient data] Jan 2, 2024 - Data Analysis and Modeling in Medicine (MIISM) - Group Hesser Jerg, Katharina, 2024, "Real-time definition of single seed placement sensitivity in low-dose-rate prostate brachytherapy [code and patient data]", https://doi.org/10.11588/data/Y3KIPM, heiDATA, V1 PURPOSE: In low-dose-rate brachytherapy iodine seeds are implanted based on a treatment plan, generated with respect to different dose constraints. The quality of the dose distribution depends on a precise seed placement, however, it is not clear which seed misplacements have a l...
Mechanical forces control the valency of the malaria adhesin VAR2CSA by exposing cryptic glycan binding sites [data] Dec 4, 2023 - HITS MBM Roessner Rita; Michelarakis, Nicholas; Gräter, Frauke; Aponte-Santamaría, Camilo, 2023, "Mechanical forces control the valency of the malaria adhesin VAR2CSA by exposing cryptic glycan binding sites [data]", https://doi.org/10.11588/data/EZHMDU, heiDATA, V1 Plasmodium falciparum (Pf) is responsible for the most lethal form of malaria. VAR2CSA is an adhesin protein expressed by this parasite at the membrane of infected erythrocytes for attachment to the placenta, leading to pregnancy-associated malaria. VAR2CSA is a large 355 kDa mul...
Data Analysis and Modeling in Medicine (MIISM) - Group Hesser(Heidelberg University, Mannheim Institute of Intelligent Systems in Medicine (MIISM)) Oct 12, 2023 The research group of Prof. Hesser focuses on the field of inverse problems. To mention a few, image reconstruction, segmentation, classification etc. play a vital role for clinical decision systems (CDS) or therapy support systems (TSS) but also for preclinical research. Deep le...
Digital Appendix: Structural cerebrocortical changes in ageing and chronic neuropathic pain - a mouse study correlating magnetic resonance imaging and in vivo two-photon microscopy Sep 29, 2023 - Functional Neuroanatomy Asan, Livia, 2023, "Digital Appendix: Structural cerebrocortical changes in ageing and chronic neuropathic pain - a mouse study correlating magnetic resonance imaging and in vivo two-photon microscopy", https://doi.org/10.11588/data/TPZWAE, heiDATA, V1, UNF:6:E5Th/vUc0jX9a3OPVhNHfQ== [fileUNF] This is the digital appendix to the dissertation by Livia Asan, titled "Structural cerebrocortical changes in ageing and chronic neuropathic pain - a mouse study correlating magnetic resonance imaging and in vivo two-photon microscopy", at the Faculty of Medicine, Heidelberg, Rup...
Primary Somatosensory Cortex Bidirectionally Modulates Sensory Gain and Nociceptive Behavior in a Layer-Specific Manner [Research Data] May 26, 2023 - Medical Biophysics Group Ziegler, Katharina; Folkard, Ross; Gonzalez, Antonio; Burghardt, Jan; Antharvedi-Goda, Sailaja; Martín-Cortecero, Jesús; Isaías-Camacho, Emilio; Kaushalya, Sanjeev; Tan, Linette Liqi; Kuner, Thomas; Acuna, Claudio; Kuner, Rohini; Mease, Rebecca; Groh, Alexander, 2023, "Primary Somatosensory Cortex Bidirectionally Modulates Sensory Gain and Nociceptive Behavior in a Layer-Specific Manner [Research Data]", https://doi.org/10.11588/data/D2O0JZ, heiDATA, V2 This dataset contains electrophysiological and behavioral data and codes underlying the figures in Ziegler, K., Folkard, R., Gonzalez, A.J. et al. Primary somatosensory cortex bidirectionally modulates sensory gain and nociceptive behavior in a layer-specific manner. Nat Commun 1...
Medical Biophysics Group (Heidelberg University, Medical Faculty Heidelberg) Mar 13, 2023 Open Research Data from Medical Biophysics Group of Prof. Alexander Groh at the Medical Faculty Heidelberg.
HITS MBM(Heidelberg Institute for Theoretical Studies) Nov 8, 2022 Data publications from the the Molecular Biomechanics (MBM) group at HITS. Shareholders of HITS are the “HITS-Stiftung”, Heidelberg University and the Karlsruhe Institute of Technology (KIT)
Bothlab(Institute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University) Sep 22, 2022 The research group focuses on the rodent hippocampus as a model system. This cortical region is centrally involved in declarative memory processes and shows pronounced and distinct patterns of network activity (e.g. gamma oscillations, sharp wave-ripples): Additionally, hippocamp...

Developmental origins and evolution of pallial cell types and structures in birds - Data

Apr 30, 2024 - Kaessmann Lab

Zaremba, Bastienne; Fallahshahroudi, Amir; Schneider, Céline; Schmidt, Julia; Sarropoulos, Ioannis; Leushkin, Evgeny; Berki, Bianka; Van Poucke, Enya; Jensen, Per; Senovilla-Ganzo, Rodrigo; Hervas-Sotomayor, Francisca; Trost, Nils; Lamanna, Francesco; Sepp, Mari; García-Moreno, Fernando; Kaessmann, Henrik, 2024, "Developmental origins and evolution of pallial cell types and structures in birds - Data", https://doi.org/10.11588/data/BX6REK, heiDATA, V1, UNF:6:4DNo7hOUtj/vCfSrVp37wA== [fileUNF]

The advanced cognitive abilities of birds rival those of mammals and have been attributed to evolutionary innovations in the pallium. However, a comprehensive cellular characterization of this brain region in birds has been lacking. We scrutinized the structures, cell types and e...

Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]

Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life

Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]

Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...

Real-time definition of single seed placement sensitivity in low-dose-rate prostate brachytherapy [code and patient data]

Jan 2, 2024 - Data Analysis and Modeling in Medicine (MIISM) - Group Hesser

Jerg, Katharina, 2024, "Real-time definition of single seed placement sensitivity in low-dose-rate prostate brachytherapy [code and patient data]", https://doi.org/10.11588/data/Y3KIPM, heiDATA, V1

PURPOSE: In low-dose-rate brachytherapy iodine seeds are implanted based on a treatment plan, generated with respect to different dose constraints. The quality of the dose distribution depends on a precise seed placement, however, it is not clear which seed misplacements have a l...

Mechanical forces control the valency of the malaria adhesin VAR2CSA by exposing cryptic glycan binding sites [data]

Dec 4, 2023 - HITS MBM

Roessner Rita; Michelarakis, Nicholas; Gräter, Frauke; Aponte-Santamaría, Camilo, 2023, "Mechanical forces control the valency of the malaria adhesin VAR2CSA by exposing cryptic glycan binding sites [data]", https://doi.org/10.11588/data/EZHMDU, heiDATA, V1

Plasmodium falciparum (Pf) is responsible for the most lethal form of malaria. VAR2CSA is an adhesin protein expressed by this parasite at the membrane of infected erythrocytes for attachment to the placenta, leading to pregnancy-associated malaria. VAR2CSA is a large 355 kDa mul...

Data Analysis and Modeling in Medicine (MIISM) - Group Hesser(Heidelberg University, Mannheim Institute of Intelligent Systems in Medicine (MIISM))

Oct 12, 2023

The research group of Prof. Hesser focuses on the field of inverse problems. To mention a few, image reconstruction, segmentation, classification etc. play a vital role for clinical decision systems (CDS) or therapy support systems (TSS) but also for preclinical research. Deep le...

Digital Appendix: Structural cerebrocortical changes in ageing and chronic neuropathic pain - a mouse study correlating magnetic resonance imaging and in vivo two-photon microscopy

Sep 29, 2023 - Functional Neuroanatomy

Asan, Livia, 2023, "Digital Appendix: Structural cerebrocortical changes in ageing and chronic neuropathic pain - a mouse study correlating magnetic resonance imaging and in vivo two-photon microscopy", https://doi.org/10.11588/data/TPZWAE, heiDATA, V1, UNF:6:E5Th/vUc0jX9a3OPVhNHfQ== [fileUNF]

This is the digital appendix to the dissertation by Livia Asan, titled "Structural cerebrocortical changes in ageing and chronic neuropathic pain - a mouse study correlating magnetic resonance imaging and in vivo two-photon microscopy", at the Faculty of Medicine, Heidelberg, Rup...

Primary Somatosensory Cortex Bidirectionally Modulates Sensory Gain and Nociceptive Behavior in a Layer-Specific Manner [Research Data]

May 26, 2023 - Medical Biophysics Group

Ziegler, Katharina; Folkard, Ross; Gonzalez, Antonio; Burghardt, Jan; Antharvedi-Goda, Sailaja; Martín-Cortecero, Jesús; Isaías-Camacho, Emilio; Kaushalya, Sanjeev; Tan, Linette Liqi; Kuner, Thomas; Acuna, Claudio; Kuner, Rohini; Mease, Rebecca; Groh, Alexander, 2023, "Primary Somatosensory Cortex Bidirectionally Modulates Sensory Gain and Nociceptive Behavior in a Layer-Specific Manner [Research Data]", https://doi.org/10.11588/data/D2O0JZ, heiDATA, V2

This dataset contains electrophysiological and behavioral data and codes underlying the figures in Ziegler, K., Folkard, R., Gonzalez, A.J. et al. Primary somatosensory cortex bidirectionally modulates sensory gain and nociceptive behavior in a layer-specific manner. Nat Commun 1...

Medical Biophysics Group (Heidelberg University, Medical Faculty Heidelberg)

Mar 13, 2023

Open Research Data from Medical Biophysics Group of Prof. Alexander Groh at the Medical Faculty Heidelberg.

HITS MBM(Heidelberg Institute for Theoretical Studies)

Nov 8, 2022

Data publications from the the Molecular Biomechanics (MBM) group at HITS. Shareholders of HITS are the “HITS-Stiftung”, Heidelberg University and the Karlsruhe Institute of Technology (KIT)

Bothlab(Institute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University)

Sep 22, 2022

The research group focuses on the rodent hippocampus as a model system. This cortical region is centrally involved in declarative memory processes and shows pronounced and distinct patterns of network activity (e.g. gamma oscillations, sharp wave-ripples): Additionally, hippocamp...

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