1 to 10 of 115 Results
Herrmann, Yannis; Lainati, Federica; del Mar Castro, María; Mwamba, Chanda; Kumwenda, Moses; Muyoyeta, Monde; Broger, Tobias; Heinrich, Norbert; Olbrich, Lisa; Corbett, Elizabeth; McMahon, Shannon; Engel, Nora; Denkinger, Claudia, 2022, "User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia [data]", https://doi.org/10.11588/data/PLRQCZ, heiDATA, V1
This data set supports the findings of the FujiLAM qualitative study published in PLOS Global Public Health (Titel:"User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia"). The repository contains our d... |
Nov 30, 2021 - Göpfrich Group - Biophysical Engineering of Life
Abele, Tobias; Messer, Tobias; Jahnke, Kevin; Hippler, Marc; Bastmeyer, Martin; Wegener, Martin; Goepfrich, Kerstin, 2021, "Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]", https://doi.org/10.11588/data/PUKJCV, heiDATA, V1
Towards the ambitious goal of manufacturing synthetic cells from the bottom up, various cellular components have already been reconstituted inside of lipid vesicles. However, the deterministic positioning of these components inside the compartment has remained elusive. Here, by u... |
Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]
Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a... |
Reitter, Sonja; Schoelz, Christian; Stoecklin, Georg, 2023, "Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes", https://doi.org/10.11588/data/M5ZUPP, heiDATA, V1
While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of riboso... |
Kong, Ka-Yiu Edwin; Fischer, Bernd; Meurer, Matthias; Kats, Ilia; Li, Zhaoyan; Rühle, Frank; Barry, Joseph D.; Kirrmaier, Daniel; Chevyreva, Veronika; San Luis, Bryan-Joseph; Costanzo, Michael; Huber, Wolfgang; Andrews, Brenda J.; Boone, Charles; Knop, Michael; Khmelinskii, Anton, 2021, "Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase [Dataset]", https://doi.org/10.11588/data/Q3TSLH, heiDATA, V1
Data accompanying the paper "Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase". |
Apr 29, 2015 - Health Economics and Health Financing
Brenner, Stephan, 2015, "The quality of clinical maternal and neonatal healthcare", https://doi.org/10.11588/data/10042, heiDATA, V2
Data was collected in a total of 33 health factilities.Data was collected by direct non-participatory observation of the clinical interactions between maternal care providers and women delivering in the factilities' maternity unit. The main purpose of the study was to determine t... |
Aug 24, 2021 - Global Health and Economics
Kohler, Stefan; Ndungwani, Rumbidzai; Burgert, Mark; Sibandze, Dumile; Matse, Sindy; Hettema, Anita, 2021, "The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]", https://doi.org/10.11588/data/KXTQTZ, heiDATA, V1
HIV treatment and prevention as well as other chronic disease care can require regular kidney function assessment based on a creatinine test. To assess the costs of creatinine testing in a public health care system, we conducted activity-based costing during a HIV pre-exposure pr... |
Apr 18, 2024 - Global Health and Economics
Kohler, Stefan; Sitali, Norman; Achar, Jay; Paul, Nicolas, 2024, "The contribution of drug import to the cost of tuberculosis treatment: a cost analysis of longer, shorter and short drug regimens for Karakalpakstan, Uzbekistan [Research Data]", https://doi.org/10.11588/data/LTTWSQ, heiDATA, V1
Tuberculosis (TB) programs depend on a continuous supply of large amounts of high-quality TB drugs. When TB programs procure TB drugs from international suppliers, such as the Global Drug Facility, they can incur import costs for international transport, customs clearance, and na... |
Apr 30, 2021 - Division of Infectious Disease and Tropical Medicine
Krüger, Lisa J.; Gaeddert, Mary; Tobian, Frank; Lainati, Federica; Gottschalk, Claudius; Klein, Julian A.F.; Schnitzler, Paul; Kräusslich, Hans-Georg; Nikolai, Olga; Lindner, Andreas K.; Mockenhaupt, Frank P.; Seybold, Joachim; Corman, Victor M.; Drosten, Christian; Pollock, Nira; Knorr, Britta; Welker, Andreas; de Vos, Margaretha; Sacks, Jilian A.; Denkinger, Claudia M., 2021, "The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2 - Evaluation of the accuracy and ease-of-use [Research Data]", https://doi.org/10.11588/data/FSPQL4, heiDATA, V1
This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab... |
Peil, Barbara; Kabisch, Maria; Fischer, Christine; Hamann, Ute; Lorenzo Bermejo, Justo, 2018, "Tailored Selection of Study Individuals to be Sequenced in Order to Improve the Accuracy of Genotype Imputation [Source Code]", https://doi.org/10.11588/data/TT4VM3, heiDATA, V1
The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombi... |
