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Subject: Medicine, Health and Life Sciences Publication Year: 2021

1 to 10 of 17 Results

Cellular development and evolution of the mammalian cerebellum [Research Data] Nov 29, 2023 - Kaessmann Lab Sepp, Mari; Leiss, Kevin; Murat, Florent; Okonechnikov, Konstantin; Joshi, Piyush; Leushkin, Evgeny; Spänig, Lisa; Mbengue, Noe; Schneider, Céline; Schmidt, Julia; Trost, Nils; Schauer, Maria; Khaitovich, Philipp; Lisgo, Steven; Palkovits, Miklós; Giere, Peter; Kutscher, Lena M.; Anders, Simon; Cardoso-Moreira, Margarida; Sarropoulos, Ioannis; Pfister, Stefan M.; Kaessmann, Henrik, 2021, "Cellular development and evolution of the mammalian cerebellum [Research Data]", https://doi.org/10.11588/data/QDOC4E, heiDATA, V3 The expansion of the neocortex, a hallmark of mammalian evolution1,2, was accompanied by an increase in cerebellar neuron numbers3. However, little is known about the evolution of the cellular programs underlying cerebellum development in mammals. In this study, we generated sing...
Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data] Nov 30, 2021 - Göpfrich Group - Biophysical Engineering of Life Abele, Tobias; Messer, Tobias; Jahnke, Kevin; Hippler, Marc; Bastmeyer, Martin; Wegener, Martin; Goepfrich, Kerstin, 2021, "Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]", https://doi.org/10.11588/data/PUKJCV, heiDATA, V1 Towards the ambitious goal of manufacturing synthetic cells from the bottom up, various cellular components have already been reconstituted inside of lipid vesicles. However, the deterministic positioning of these components inside the compartment has remained elusive. Here, by u...
Measurement Performance of Activity Measurements with Newer Generation of Apple Watch in Wheelchair Users with Spinal Cord Injury: Manually and Device-Counted Pushes [Data] Nov 17, 2021 - Medical Informatics Benning, Nils-Hendrik; Knaup, Petra; Rupp, Rüdiger, 2021, "Measurement Performance of Activity Measurements with Newer Generation of Apple Watch in Wheelchair Users with Spinal Cord Injury: Manually and Device-Counted Pushes [Data]", https://doi.org/10.11588/data/P1HEGO, heiDATA, V1, UNF:6:br0+tP0XWfzu+FGO7V4qLw== [fileUNF] This dataset contains the results (manually counted pushes and pushes counted by Apple Watch Series 4) of the study presented in the paper "Accuracy of Activity Measurements with Newer Generations of Apple Watch in Wheelchair Users with Spinal Cord Injury”
Let the team fix it? - Performance and mood of depressed workers and coworkers in different work contexts [Research data] Sep 24, 2021 - AWI Experimental Economics Vollmann, Martin; Schwieren, Christiane; Mattern, Margarete; Schnell, Knut, 2021, "Let the team fix it? - Performance and mood of depressed workers and coworkers in different work contexts [Research data]", https://doi.org/10.11588/data/PRQILA, heiDATA, V1 Depression in the workplace is a significant factor for reduced personal well-being and productivity. Consequently, this has negative effects on the economic success of the companies in which depressed people are employed. In addition, the economy has to deal with the significant...
Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data] Sep 23, 2021 - 3D Matter Made to Order (3DMM2O) de Buhr, Svenja; Gräter, Frauke, 2021, "Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data]", https://doi.org/10.11588/data/3NKHAY, heiDATA, V1 This dataset contains input structures and parameters for coarse-grained molecular dynamics simulation of SAS-6 protein oligomers as well as post-processing files and analysis scripts. Abstract of related publication: Discovering mechanisms governing organelle assembly is a funda...
A framework for assessing import costs of medical supplies and results for a tuberculosis program in Karakalpakstan, Uzbekistan [Research Data] Sep 7, 2021 - Global Health and Economics Kohler, Stefan; Sitali, Norman; Paul, Nicolas, 2021, "A framework for assessing import costs of medical supplies and results for a tuberculosis program in Karakalpakstan, Uzbekistan [Research Data]", https://doi.org/10.11588/data/JM2H6I, heiDATA, V1, UNF:6:BWxSViGhUpB/lzuDDa3q/A== [fileUNF] Background: Import of medical supplies is common, but limited knowledge about import costs and their structure introduces uncertainty to budget planning, cost management, and cost-effectiveness analysis of health programs. We aimed to estimate the import costs of a tuberculosis (...
How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations [Research Data] Aug 25, 2021 - Institute of Medical Psychology Stoffel, Martin; Neubauer, Andreas; Ditzen, Beate, 2021, "How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations [Research Data]", https://doi.org/10.11588/data/7IWYPF, heiDATA, V1, UNF:6:46/P+TiqxKR1sw+CFKopcw== [fileUNF] The data and scripts accompany the following manuscript: "How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations". To use the data with the R scripts, we recommend downloading them in their original file format...
The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data] Aug 24, 2021 - Global Health and Economics Kohler, Stefan; Ndungwani, Rumbidzai; Burgert, Mark; Sibandze, Dumile; Matse, Sindy; Hettema, Anita, 2021, "The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]", https://doi.org/10.11588/data/KXTQTZ, heiDATA, V1 HIV treatment and prevention as well as other chronic disease care can require regular kidney function assessment based on a creatinine test. To assess the costs of creatinine testing in a public health care system, we conducted activity-based costing during a HIV pre-exposure pr...
Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset] Jul 27, 2021 - Institute of Pathology Mannheim Runz, Marlen; Weis, Cleo-Aron, 2021, "Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset]", https://doi.org/10.11588/data/8LKEZF, heiDATA, V1 Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University....
Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data] Jul 16, 2021 - Division of Infectious Disease and Tropical Medicine Krüger, Lisa Johanna; Tobian, Frank; Gaeddert, Mary; Lainati, Federica; Klein, Julian A.F.; Schnitzler, Paul; Lindner, Andreas K.; Mockenhaupt, Frank P.; Nikolai, Olga; Seybold, Joachim; Corman, Victor M.; Drosten, Christian; Knorr, Britta; Welker, Andreas; de Vos, Margaretha; Sacks, Jilian A.; Denkinger, Claudia M., 2021, "Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data]", https://doi.org/10.11588/data/D0ACC0, heiDATA, V1 This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab...

Cellular development and evolution of the mammalian cerebellum [Research Data]

Nov 29, 2023 - Kaessmann Lab

Sepp, Mari; Leiss, Kevin; Murat, Florent; Okonechnikov, Konstantin; Joshi, Piyush; Leushkin, Evgeny; Spänig, Lisa; Mbengue, Noe; Schneider, Céline; Schmidt, Julia; Trost, Nils; Schauer, Maria; Khaitovich, Philipp; Lisgo, Steven; Palkovits, Miklós; Giere, Peter; Kutscher, Lena M.; Anders, Simon; Cardoso-Moreira, Margarida; Sarropoulos, Ioannis; Pfister, Stefan M.; Kaessmann, Henrik, 2021, "Cellular development and evolution of the mammalian cerebellum [Research Data]", https://doi.org/10.11588/data/QDOC4E, heiDATA, V3

The expansion of the neocortex, a hallmark of mammalian evolution1,2, was accompanied by an increase in cerebellar neuron numbers3. However, little is known about the evolution of the cellular programs underlying cerebellum development in mammals. In this study, we generated sing...

Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]

Nov 30, 2021 - Göpfrich Group - Biophysical Engineering of Life

Abele, Tobias; Messer, Tobias; Jahnke, Kevin; Hippler, Marc; Bastmeyer, Martin; Wegener, Martin; Goepfrich, Kerstin, 2021, "Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]", https://doi.org/10.11588/data/PUKJCV, heiDATA, V1

Towards the ambitious goal of manufacturing synthetic cells from the bottom up, various cellular components have already been reconstituted inside of lipid vesicles. However, the deterministic positioning of these components inside the compartment has remained elusive. Here, by u...

Measurement Performance of Activity Measurements with Newer Generation of Apple Watch in Wheelchair Users with Spinal Cord Injury: Manually and Device-Counted Pushes [Data]

Nov 17, 2021 - Medical Informatics

Benning, Nils-Hendrik; Knaup, Petra; Rupp, Rüdiger, 2021, "Measurement Performance of Activity Measurements with Newer Generation of Apple Watch in Wheelchair Users with Spinal Cord Injury: Manually and Device-Counted Pushes [Data]", https://doi.org/10.11588/data/P1HEGO, heiDATA, V1, UNF:6:br0+tP0XWfzu+FGO7V4qLw== [fileUNF]

This dataset contains the results (manually counted pushes and pushes counted by Apple Watch Series 4) of the study presented in the paper "Accuracy of Activity Measurements with Newer Generations of Apple Watch in Wheelchair Users with Spinal Cord Injury”

Let the team fix it? - Performance and mood of depressed workers and coworkers in different work contexts [Research data]

Sep 24, 2021 - AWI Experimental Economics

Vollmann, Martin; Schwieren, Christiane; Mattern, Margarete; Schnell, Knut, 2021, "Let the team fix it? - Performance and mood of depressed workers and coworkers in different work contexts [Research data]", https://doi.org/10.11588/data/PRQILA, heiDATA, V1

Depression in the workplace is a significant factor for reduced personal well-being and productivity. Consequently, this has negative effects on the economic success of the companies in which depressed people are employed. In addition, the economy has to deal with the significant...

Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data]

Sep 23, 2021 - 3D Matter Made to Order (3DMM2O)

de Buhr, Svenja; Gräter, Frauke, 2021, "Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data]", https://doi.org/10.11588/data/3NKHAY, heiDATA, V1

This dataset contains input structures and parameters for coarse-grained molecular dynamics simulation of SAS-6 protein oligomers as well as post-processing files and analysis scripts. Abstract of related publication: Discovering mechanisms governing organelle assembly is a funda...

A framework for assessing import costs of medical supplies and results for a tuberculosis program in Karakalpakstan, Uzbekistan [Research Data]

Sep 7, 2021 - Global Health and Economics

Kohler, Stefan; Sitali, Norman; Paul, Nicolas, 2021, "A framework for assessing import costs of medical supplies and results for a tuberculosis program in Karakalpakstan, Uzbekistan [Research Data]", https://doi.org/10.11588/data/JM2H6I, heiDATA, V1, UNF:6:BWxSViGhUpB/lzuDDa3q/A== [fileUNF]

Background: Import of medical supplies is common, but limited knowledge about import costs and their structure introduces uncertainty to budget planning, cost management, and cost-effectiveness analysis of health programs. We aimed to estimate the import costs of a tuberculosis (...

How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations [Research Data]

Aug 25, 2021 - Institute of Medical Psychology

Stoffel, Martin; Neubauer, Andreas; Ditzen, Beate, 2021, "How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations [Research Data]", https://doi.org/10.11588/data/7IWYPF, heiDATA, V1, UNF:6:46/P+TiqxKR1sw+CFKopcw== [fileUNF]

The data and scripts accompany the following manuscript: "How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations". To use the data with the R scripts, we recommend downloading them in their original file format...

The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]

Aug 24, 2021 - Global Health and Economics

Kohler, Stefan; Ndungwani, Rumbidzai; Burgert, Mark; Sibandze, Dumile; Matse, Sindy; Hettema, Anita, 2021, "The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]", https://doi.org/10.11588/data/KXTQTZ, heiDATA, V1

HIV treatment and prevention as well as other chronic disease care can require regular kidney function assessment based on a creatinine test. To assess the costs of creatinine testing in a public health care system, we conducted activity-based costing during a HIV pre-exposure pr...

Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset]

Jul 27, 2021 - Institute of Pathology Mannheim

Runz, Marlen; Weis, Cleo-Aron, 2021, "Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset]", https://doi.org/10.11588/data/8LKEZF, heiDATA, V1

Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University....

Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data]

Jul 16, 2021 - Division of Infectious Disease and Tropical Medicine

Krüger, Lisa Johanna; Tobian, Frank; Gaeddert, Mary; Lainati, Federica; Klein, Julian A.F.; Schnitzler, Paul; Lindner, Andreas K.; Mockenhaupt, Frank P.; Nikolai, Olga; Seybold, Joachim; Corman, Victor M.; Drosten, Christian; Knorr, Britta; Welker, Andreas; de Vos, Margaretha; Sacks, Jilian A.; Denkinger, Claudia M., 2021, "Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data]", https://doi.org/10.11588/data/D0ACC0, heiDATA, V1

This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab...

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