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Kong, Ka-Yiu Edwin; Fischer, Bernd; Meurer, Matthias; Kats, Ilia; Li, Zhaoyan; Rühle, Frank; Barry, Joseph D.; Kirrmaier, Daniel; Chevyreva, Veronika; San Luis, Bryan-Joseph; Costanzo, Michael; Huber, Wolfgang; Andrews, Brenda J.; Boone, Charles; Knop, Michael; Khmelinskii, Anton, 2021, "Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase [Dataset]", https://doi.org/10.11588/data/Q3TSLH, heiDATA, V1
Data accompanying the paper "Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase". |
Aug 24, 2021 - Global Health and Economics
Kohler, Stefan; Ndungwani, Rumbidzai; Burgert, Mark; Sibandze, Dumile; Matse, Sindy; Hettema, Anita, 2021, "The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]", https://doi.org/10.11588/data/KXTQTZ, heiDATA, V1
HIV treatment and prevention as well as other chronic disease care can require regular kidney function assessment based on a creatinine test. To assess the costs of creatinine testing in a public health care system, we conducted activity-based costing during a HIV pre-exposure pr... |
Apr 30, 2021 - Division of Infectious Disease and Tropical Medicine
Krüger, Lisa J.; Gaeddert, Mary; Tobian, Frank; Lainati, Federica; Gottschalk, Claudius; Klein, Julian A.F.; Schnitzler, Paul; Kräusslich, Hans-Georg; Nikolai, Olga; Lindner, Andreas K.; Mockenhaupt, Frank P.; Seybold, Joachim; Corman, Victor M.; Drosten, Christian; Pollock, Nira; Knorr, Britta; Welker, Andreas; de Vos, Margaretha; Sacks, Jilian A.; Denkinger, Claudia M., 2021, "The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2 - Evaluation of the accuracy and ease-of-use [Research Data]", https://doi.org/10.11588/data/FSPQL4, heiDATA, V1
This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab... |
Peil, Barbara; Kabisch, Maria; Fischer, Christine; Hamann, Ute; Lorenzo Bermejo, Justo, 2018, "Tailored Selection of Study Individuals to be Sequenced in Order to Improve the Accuracy of Genotype Imputation [Source Code]", https://doi.org/10.11588/data/TT4VM3, heiDATA, V1
The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombi... |
Oct 5, 2018 - Statistical Genetics
Lorenzo Bermejo, Justo; Boekstegers, Felix; González Silos, Rosa; Marcelain, Katherine; Baez Benavides, Pablo; Barahona Ponce, Carol; Müller, Bettina; Ferreccio, Catterina; Koshiol, Jill; Fischer, Christine; Peil, Barbara; Sinsheimer,Janet; Fuentes Guajardo,Macarena; Barajas, Olga; Gonzalez-Jose, Rolando; Bedoya, Gabriel; Cátira Bortolini, Maria; Canizales-Quinteros,Samuel; Gallo, Carla; Ruiz Linares, Andres; Rothhammer, Francisco, 2018, "Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile [Dataset]", https://doi.org/10.11588/data/IDSI88, heiDATA, V1
Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and disease prevention. Here we investigate possible association... |
Hausmann, Michael; Müller, Patrick; Hillebrandt, Sabina; Bach, Margund; Kaufmann, Rainer; Zhang, Yang, 2015, "SPDM data capturing radiation induced chromatin conformation changes", https://doi.org/10.11588/data/10031, heiDATA, V3
Using stably transfected HeLa cells expressing either green fluorescent protein (GFP) labelled histone H2B or yellow fluorescent protein (YFP) labelled histone H2A, we investigated the positioning of individual histone proteins in cell nuclei by means of high resolution localizat... |
Jun 15, 2022 - Forschungsgruppe AG Nikendei
Ivo Rollmann, 2022, "Social and Cognitive Congruence [Data]", https://doi.org/10.11588/data/GEEBLZ, heiDATA, V1, UNF:6:0usUjPJ6fAea5SEs9INPAw== [fileUNF]
This dataset contains the R-Script of our Evaluation and the dataset on which our results are based. |
Kesselmeier, Miriam; Lorenzo Bermejo, Justo, 2018, "Robust logistic regression to narrow down the winner's curse for rare and recessive susceptibility variants [Source Code]", https://doi.org/10.11588/data/0Z7H1X, heiDATA, V1
Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unus... |
Vardarli, Irfan; Tan, Susanne; Brandenburg, Tim; Weidemann, Frank; Görges, Rainer; Herrmann, Ken; Führer, Dagmar, 2023, "Risk and incidence of endocrine immune related adverse effects under checkpoint inhibitor mono or combination therapy in solid tumors: a meta-analysis of randomized controlled trials [data]", https://doi.org/10.11588/data/AWIFGR, heiDATA, V1, UNF:6:qBMlvagCg7J7FP6FCbo+5Q== [fileUNF]
Supplemental Materials Abstract Context Few meta-analyses regarding the incidence of endocrine immune related adverse effects (eirAEs) have been published and many trials were published thereafter. Objective To assess the risk and incidence of eirAEs of any grade and grade 3-5 by... |
Huber, Florian; Bunina, Daria; Gupta, Ishaan; Khmelinski, Anton; Meurer, Matthias; Theer, Patrick; Steinmetz, Lars M.; Knop, Michael, 2016, "Protein abundance control by non-coding antisense transcription [Dataset]", https://doi.org/10.11588/data/10073, heiDATA, V4
Data accompanying the paper "Protein abundance control by non-coding antisense transcription" by Huber et al, 2016, Cell Reports. This contains FACS data for the noise analysis in the publication as well as single cell data from microscopy. |
