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41 to 50 of 115 Results
Mar 2, 2023 - AG Computational Diagnostic
Kriegsmann, Katharina; Lobers, Fritjof; Zgorzelski, Christiane; Kriegsmann, Jörg; Meliß, Rolf Rüdiger; Sack, Ulrich; Steinbuss,Georg; Kriegsmann,Mark, 2023, "Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections [data]", https://doi.org/10.11588/data/7QCR8S, heiDATA, V1
Basal cell carcinoma (BCC), squamous cell carcinoma (SqCC) and melanoma are among the most common cancer types. Correct diagnosis based on histological evaluation after biopsy or excision is paramount for adequate therapy stratification. Deep learning on histological slides has b...
Feb 23, 2023 - Heidelberg Pain Consortium - SFB 1158
Oswald, Manfred Josef; Beretta, Carlo Antonio; Stegemann, Alina; Han, Yechao; Kuner, Rohini, 2023, "Prefrontal engrams of long-term fear memory and pain", https://doi.org/10.11588/data/VEEIDP, heiDATA, V1, UNF:6:QT9272Lmh0bGgVxcezQ+yw== [fileUNF]
This dataset contains electrophysiological spike time data and associated analysis procedures as well as image analysis scripts reported in Stegemann et al. Prefrontal engrams of long-term fear memory perpetuate pain perception. Nature Neuroscience (2023). Abstract: A painful epi...
Feb 20, 2023 - Stoecklin_BCH_MI3
Reitter, Sonja; Schoelz, Christian; Stoecklin, Georg, 2023, "Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes", https://doi.org/10.11588/data/M5ZUPP, heiDATA, V1
While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of riboso...
Feb 15, 2023 - HITS MBM
Buhr, Jannik; Franz, Florian; Gräter, Frauke, 2023, "Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data]", https://doi.org/10.11588/data/BQTQUN, heiDATA, V1
Focal adhesions (FAs) mediate the interaction of the cytoskeleton with the extracellular matrix (ECM) in a highly dynamic fashion. talin is a central regulator, adaptor protein and mechano-sensor of focal adhesion complexes. For recruitment and firm attachment at FAs, talin’s N-t...
Feb 6, 2023 - Forschungsgruppe AG Nikendei
Nowak, Jonathan; Rollmann, Ivo; Kindermann, David; Nikendei, Christoph, 2023, "Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis]", https://doi.org/10.11588/data/W63LJJ, heiDATA, V1
This dataset contains the code for the analysis in R which was used to calculate the results for the study 'Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sam...
Jan 17, 2023 - NCT - Section of Translational Medical Ethics
Köngeter, Anja; Schickhardt, Christoph; Jungkunz, Martin; Mehlis, Katja; Winkler, Eva C., 2022, "Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data]", https://doi.org/10.11588/data/5JCEVW, heiDATA, V2, UNF:6:rCJxTnlT0ZCX6/Tn/Zv78g== [fileUNF]
This is the research data from the publication "Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey." The research data includes the questionnaire, the data set used, and a description of the data preparat...
Sep 22, 2022 - Bothlab
Hodapp, Alexander; Kaiser, Martin E.; Thome, Christian; Ding, Lingjun; Rozov, Andrei; Klumpp, Matthias; Stevens, Nikolas; Stingl, Moritz; Sackmann, Tina; Lehmann, Nadja; Draguhn, Andreas; Burgalossi, Andrea; Engelhardt, Maren; Both, Martin, 2022, "Activity of AcD and nonAcD cells during high-frequency network oscillations [data]", https://doi.org/10.11588/data/JWLFFZ, heiDATA, V1, UNF:6:IbIOEy1OPRgP05Qd2QIN4w== [fileUNF]
Information processing in neuronal networks involves the recruitment of selected neurons into coordinated spatiotemporal activity patterns. This sparse activation results from widespread synaptic inhibition in conjunction with neuron-specific synaptic excitation. We report the se...
Aug 23, 2022 - Institute of Medical Psychology
Hopf, Dora; Schneider, Ekaterina; Ditzen, Beate; Eckstein, Monika, 2022, "Loneliness and diurnal cortisol levels during COVID-19 lockdown: the roles of living situation, relationship status and relationship quality [Research Data]", https://doi.org/10.11588/data/SYVQMM, heiDATA, V1, UNF:6:ASynYjAnlwnyKYrcI2WbFg== [fileUNF]
These data accompany the manuscript "Loneliness and diurnal cortisol levels during COVID-19 lockdown: the roles of living situation, relationship status and relationship quality". Abstract: Loneliness and social isolation have become increasing concerns during COVID-19 lockdown t...
Aug 2, 2022 - NCT - Section of Translational Medical Ethics
Anger, Michael; Wendelborn, Christian; Winkler, Eva; Schickhardt, Christoph, 2022, "Neither Carrots nor Sticks? Challenges surrounding Data Sharing from the Perspective of Research Funding Agencies – A Qualitative Expert Interview Study [Interview Excerpts]", https://doi.org/10.11588/data/M2TSIT, heiDATA, V1
This dataset contains summaries from interviews with data sharing experts from internationa funding agencies on their organisation's data sharing policy. Data Sharing is widely recognised as crucial for accelerating scientific research and improving its quality. However, data sha...
Aug 2, 2022 - Computer Assisted Clinical Medicine
Brumer, Irene, 2022, "Synthetic renal ASL MRI [data]", https://doi.org/10.11588/data/QAHWSF, heiDATA, V1
Synthetic renal ASL data sets simulating in-vivo acquisitions were generated using body models from the XCAT phantom, the general kinetic model and literature values for tissue properties. Sequence and ASL parameters were set in accordance with the current renal ASL consensus. Fi...
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