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Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data]
Dec 14, 2023
Lindner, Holger A.; Schäfer, Noah; Hahn, Bianka; Schefzik, Roman; Velásquez, Sonia Y.; Schulte, Jutta; Fudrer, Tanja; Centner, Franz-Simon; Schöttler, Jochen J.; Himmelhan, Bianca S.; Sturm, Timo; Thiel, Manfred; Schneider-Lindner, verena; Coulibaly, Anna, 2023, "Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data]", https://doi.org/10.11588/data/4Z4CY3, heiDATA, V1, UNF:6:yxeE0siVL+Y/KFepT7ueug== [fileUNF]
Background: Pneumonia develops frequently after major surgery and polytrauma, and in the presence of systemic inflammatory response syndrome (SIRS) and organ dysfunction. Immune checkpoints balance self-tolerance and immune activation. Altered checkpoint blood levels were reporte...
Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission
May 30, 2022
Lindner, Holger, 2022, "Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission", https://doi.org/10.11588/data/EIXOPN, heiDATA, V1, UNF:6:ZU8BBGGans0NwnKgxMjy8w== [fileUNF]
Background: Infection can induce granulopoiesis. This process potentially gives rise to blood gene classifiers of sepsis in systemic inflammatory response syndrome (SIRS) patients. The aim of this study was to identify sepsis signature genes in blood granulocytes from patients wi...
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