AG Lindner - Experimental Anesthesiology

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1 to 9 of 9 Results

Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data] Dec 14, 2023 Lindner, Holger A.; Schäfer, Noah; Hahn, Bianka; Schefzik, Roman; Velásquez, Sonia Y.; Schulte, Jutta; Fudrer, Tanja; Centner, Franz-Simon; Schöttler, Jochen J.; Himmelhan, Bianca S.; Sturm, Timo; Thiel, Manfred; Schneider-Lindner, verena; Coulibaly, Anna, 2023, "Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data]", https://doi.org/10.11588/data/4Z4CY3, heiDATA, V1, UNF:6:yxeE0siVL+Y/KFepT7ueug== [fileUNF] Background: Pneumonia develops frequently after major surgery and polytrauma, and in the presence of systemic inflammatory response syndrome (SIRS) and organ dysfunction. Immune checkpoints balance self-tolerance and immune activation. Altered checkpoint blood levels were reporte...
Bead array results_Non-polytrauma.tab Dec 14, 2023 - Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data] Tabular Data - 2.3 KB - 6 Variables, 56 Observations - UNF:6:3UsUzgcHbGBD+bVRvxDYSw== Study baseline blood levels of HVEM and ICOS in polytrauma and non-polytrauma patients with and without sepsis.
Bead array results_Polytrauma.tab Dec 14, 2023 - Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data] Tabular Data - 42.5 KB - 83 Variables, 78 Observations - UNF:6:Crlgq5uxtsp92GHrXEsUIQ== Time trends of immune checkpoint blood levels in polytrauma patients with pneumonia and without infection.
Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission May 30, 2022 Lindner, Holger, 2022, "Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission", https://doi.org/10.11588/data/EIXOPN, heiDATA, V1, UNF:6:ZU8BBGGans0NwnKgxMjy8w== [fileUNF] Background: Infection can induce granulopoiesis. This process potentially gives rise to blood gene classifiers of sepsis in systemic inflammatory response syndrome (SIRS) patients. The aim of this study was to identify sepsis signature genes in blood granulocytes from patients wi...
Clinical phenotype_CD15_RNA preparation characteristics cell_counts.tab May 30, 2022 - Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission Tabular Data - 54.2 KB - 67 Variables, 262 Observations - UNF:6:VPnuYW+1kKhFj7yZqZ9ZUg==
Differentially expressed genes_Discovery.tab May 30, 2022 - Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission Tabular Data - 11.4 MB - 63 Variables, 6730 Observations - UNF:6:S+uYDVJeqnqRAuFIqiT6ig==
Pathway enrichment_Discovery.zip May 30, 2022 - Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission ZIP Archive - 39.1 MB - MD5: e9dd8987d27003e22ed3755a7868b450
QuantiGene Plex_Validation subset A.tab May 30, 2022 - Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission Tabular Data - 19.4 KB - 59 Variables, 40 Observations - UNF:6:tU3p8gAjCvoW0QOx6HOqLg==
QuantiGene Plex_Validation subset B.tab May 30, 2022 - Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission Tabular Data - 40.4 KB - 72 Variables, 32 Observations - UNF:6:dJfmZHZt+MWMhMnB/FG1EQ==

Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data]

Dec 14, 2023

Lindner, Holger A.; Schäfer, Noah; Hahn, Bianka; Schefzik, Roman; Velásquez, Sonia Y.; Schulte, Jutta; Fudrer, Tanja; Centner, Franz-Simon; Schöttler, Jochen J.; Himmelhan, Bianca S.; Sturm, Timo; Thiel, Manfred; Schneider-Lindner, verena; Coulibaly, Anna, 2023, "Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data]", https://doi.org/10.11588/data/4Z4CY3, heiDATA, V1, UNF:6:yxeE0siVL+Y/KFepT7ueug== [fileUNF]

Background: Pneumonia develops frequently after major surgery and polytrauma, and in the presence of systemic inflammatory response syndrome (SIRS) and organ dysfunction. Immune checkpoints balance self-tolerance and immune activation. Altered checkpoint blood levels were reporte...

Bead array results_Non-polytrauma.tab

Dec 14, 2023 - Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data]

Tabular Data - 2.3 KB - 6 Variables, 56 Observations -

Study baseline blood levels of HVEM and ICOS in polytrauma and non-polytrauma patients with and without sepsis.

Bead array results_Polytrauma.tab

Dec 14, 2023 - Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble HVEM [research data]

Tabular Data - 42.5 KB - 83 Variables, 78 Observations -

Time trends of immune checkpoint blood levels in polytrauma patients with pneumonia and without infection.

Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission

May 30, 2022

Lindner, Holger, 2022, "Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission", https://doi.org/10.11588/data/EIXOPN, heiDATA, V1, UNF:6:ZU8BBGGans0NwnKgxMjy8w== [fileUNF]

Background: Infection can induce granulopoiesis. This process potentially gives rise to blood gene classifiers of sepsis in systemic inflammatory response syndrome (SIRS) patients. The aim of this study was to identify sepsis signature genes in blood granulocytes from patients wi...

Clinical phenotype_CD15_RNA preparation characteristics cell_counts.tab

May 30, 2022 - Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission

Tabular Data - 54.2 KB - 67 Variables, 262 Observations -

Differentially expressed genes_Discovery.tab

May 30, 2022 - Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission

Tabular Data - 11.4 MB - 63 Variables, 6730 Observations -

Pathway enrichment_Discovery.zip

May 30, 2022 - Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission

ZIP Archive - 39.1 MB -

QuantiGene Plex_Validation subset A.tab

May 30, 2022 - Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission

Tabular Data - 19.4 KB - 59 Variables, 40 Observations -