3D Matter Made to Order (3DMM2O)

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Subject: Medicine, Health and Life Sciences

1 to 6 of 6 Results

A Minimalistic, Synthetic Cell-Inspired Metamaterial for Enabling Reversible Strain-Stiffening [data] May 1, 2024 Taale, Mohammadreza, 2024, "A Minimalistic, Synthetic Cell-Inspired Metamaterial for Enabling Reversible Strain-Stiffening [data]", https://doi.org/10.11588/data/MNMLVX, heiDATA, V2 Strain-stiffening, i.e. the nonlinear stiffening of a material in response to a strain, is an intrinsic feature of many biological systems, including skin, blood vessels, and single cells. To avoid a mismatch in mechanical properties, synthetic materials in contact with such biol...
Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data] Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF] Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...
Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA] Feb 28, 2022 - Göpfrich Group - Biophysical Engineering of Life Goepfrich, Kerstin; Walther, Tobias, 2022, "Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]", https://doi.org/10.11588/data/MKOC9S, heiDATA, V1 In the pursuit to produce functioning synthetic cells from the bottom up, DNA nanotechnology has proven to be a powerful tool. However, the crowded yet highly organized arrangement in living cells, bridging from the nano- to the micron-scale, remains challenging to recreate with...
Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data] Nov 30, 2021 - Göpfrich Group - Biophysical Engineering of Life Abele, Tobias; Messer, Tobias; Jahnke, Kevin; Hippler, Marc; Bastmeyer, Martin; Wegener, Martin; Goepfrich, Kerstin, 2021, "Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]", https://doi.org/10.11588/data/PUKJCV, heiDATA, V1 Towards the ambitious goal of manufacturing synthetic cells from the bottom up, various cellular components have already been reconstituted inside of lipid vesicles. However, the deterministic positioning of these components inside the compartment has remained elusive. Here, by u...
Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data] Sep 23, 2021 de Buhr, Svenja; Gräter, Frauke, 2021, "Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data]", https://doi.org/10.11588/data/3NKHAY, heiDATA, V1 This dataset contains input structures and parameters for coarse-grained molecular dynamics simulation of SAS-6 protein oligomers as well as post-processing files and analysis scripts. Abstract of related publication: Discovering mechanisms governing organelle assembly is a funda...
Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development - in vivo imaging of OV formation Jul 6, 2021 - AG Wittbrodt Zilova, Lucie; Weinhardt, Venera; Tavhelidse, Tinatini; Schlagheck, Christina; Thumberger, Thomas; Wittbrodt, Joachim, 2021, "Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development - in vivo imaging of OV formation", https://doi.org/10.11588/data/AOSUS8, heiDATA, V1 Development of a functional retina is accompanied by several morphological events transitions that ultimately result in the formation of a functional retina. One of them is the formation of the OV. When fish-derived organoids were generated with reduced cell-seeding density by 50...

A Minimalistic, Synthetic Cell-Inspired Metamaterial for Enabling Reversible Strain-Stiffening [data]

May 1, 2024

Taale, Mohammadreza, 2024, "A Minimalistic, Synthetic Cell-Inspired Metamaterial for Enabling Reversible Strain-Stiffening [data]", https://doi.org/10.11588/data/MNMLVX, heiDATA, V2

Strain-stiffening, i.e. the nonlinear stiffening of a material in response to a strain, is an intrinsic feature of many biological systems, including skin, blood vessels, and single cells. To avoid a mismatch in mechanical properties, synthetic materials in contact with such biol...

Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]

Feb 16, 2024 - Göpfrich Group - Biophysical Engineering of Life

Illig, Maja; Jahnke, Kevin; Weise, Lukas P.; Scheffold, Marlene; Mersdorf, Ulrike; Drechsler, Hauke; Zhang, Yixin; Diez, Stefan; Kierfeld, Jan; Göpfrich, Kerstin, 2024, "Triggered contraction of self-assembled micron-scale DNA nanotube rings [Research Data]", https://doi.org/10.11588/data/ADYUNN, heiDATA, V1, UNF:6:AJdXI51lTUqvs4V/XCVPZQ== [fileUNF]

Contractile rings formed from cytoskeletal filaments mediate the division of cells. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes as mimics of cytoskeletal filaments and a...

Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]

Feb 28, 2022 - Göpfrich Group - Biophysical Engineering of Life

Goepfrich, Kerstin; Walther, Tobias, 2022, "Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]", https://doi.org/10.11588/data/MKOC9S, heiDATA, V1

In the pursuit to produce functioning synthetic cells from the bottom up, DNA nanotechnology has proven to be a powerful tool. However, the crowded yet highly organized arrangement in living cells, bridging from the nano- to the micron-scale, remains challenging to recreate with...

Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]

Nov 30, 2021 - Göpfrich Group - Biophysical Engineering of Life

Abele, Tobias; Messer, Tobias; Jahnke, Kevin; Hippler, Marc; Bastmeyer, Martin; Wegener, Martin; Goepfrich, Kerstin, 2021, "Two-Photon 3D Laser Printing Inside Synthetic Cells [Research Data]", https://doi.org/10.11588/data/PUKJCV, heiDATA, V1

Towards the ambitious goal of manufacturing synthetic cells from the bottom up, various cellular components have already been reconstituted inside of lipid vesicles. However, the deterministic positioning of these components inside the compartment has remained elusive. Here, by u...

Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data]

Sep 23, 2021

de Buhr, Svenja; Gräter, Frauke, 2021, "Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data]", https://doi.org/10.11588/data/3NKHAY, heiDATA, V1

This dataset contains input structures and parameters for coarse-grained molecular dynamics simulation of SAS-6 protein oligomers as well as post-processing files and analysis scripts. Abstract of related publication: Discovering mechanisms governing organelle assembly is a funda...

Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development - in vivo imaging of OV formation

Jul 6, 2021 - AG Wittbrodt

Zilova, Lucie; Weinhardt, Venera; Tavhelidse, Tinatini; Schlagheck, Christina; Thumberger, Thomas; Wittbrodt, Joachim, 2021, "Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development - in vivo imaging of OV formation", https://doi.org/10.11588/data/AOSUS8, heiDATA, V1

Development of a functional retina is accompanied by several morphological events transitions that ultimately result in the formation of a functional retina. One of them is the formation of the OV. When fish-derived organoids were generated with reduced cell-seeding density by 50...

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