Persistent Identifier
|
doi:10.11588/data/D0ACC0 |
Publication Date
|
2021-07-16 |
Title
| Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data] |
Other Identifier
| Heidelberg University Hospital |
Author
| Krüger, Lisa Johanna (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)
Tobian, Frank (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)
Gaeddert, Mary (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)
Lainati, Federica (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)
Klein, Julian A.F. (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)
Schnitzler, Paul (Virology, Heidelberg University Hospital)
Lindner, Andreas K. (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Tropical Medicine and International Health)
Mockenhaupt, Frank P. (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Tropical Medicine and International Health)
Nikolai, Olga (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Tropical Medicine and International Health)
Seybold, Joachim (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Medical Directorate)
Corman, Victor M. (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Virology)
Drosten, Christian (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Virology)
Knorr, Britta (Department of Public Health Rhein Neckar Region)
Welker, Andreas (Department of Public Health Rhein Neckar Region)
de Vos, Margaretha (Foundation for Innovative New Diagnostics)
Sacks, Jilian A. (Foundation for Innovative New Diagnostics)
Denkinger, Claudia M. (Division of Clinical Tropical Medicine, Heidelberg University Hospital, Heidelberg) |
Point of Contact
|
Use email button above to contact.
Tobian, Frank (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany) |
Description
| This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab was performed for Ag-RDT testing. Routine swabs were nasopharyngeal (NP) or combined NP/oropharyngeal (OP) whereas the study-exclusive swabs were NP. To evaluate performance, sensitivity and specificity were assessed overall and in predefined sub analyses accordingly to viral load, days of symptoms and symptoms. In addition, further data from the participants were collected during interviews (2021-07-16) |
Subject
| Medicine, Health and Life Sciences |
Keyword
| antigen-detecting rapid tests
SARS-CoV-2
Covid-19
Diagnostics |
Topic Classification
| Antigen-detecting diagnostics for SARS-CoV-2 |
Related Publication
| Head-to-head comparison of SARS-CoV-2 antigen-detecting rapid test with self-collected anterior nasal swab versus professional-collected nasopharyngeal swab Andreas K. Lindner, Olga Nikolai, Franka Kausch, Mia Wintel, Franziska Hommes, Maximilian Gertler, Lisa J. Krüger, Mary Gaeddert, Frank Tobian, Federica Lainati, Lisa Köppel, Joachim Seybold, Victor M. Corman, Christian Drosten, Jörg Hofmann, Jilian A. Sacks, Frank P. Mockenhaupt, Claudia M. Denkinger European Respiratory Journal Jan 2020, 2003961; DOI: 10.1183/13993003.03961-2020 doi: https://doi.org/10.1183/13993003.03961-2020 https://doi.org/10.1183/13993003.03961-2020
Head-to-head comparison of SARS-CoV-2 antigen-detecting rapid test with professional-collected nasal versus nasopharyngeal swab Andreas K. Lindner, Olga Nikolai, Chiara Rohardt, Susen Burock, Claudia Hülso, Alisa Bölke, Maximilian Gertler, Lisa J. Krüger, Mary Gaeddert, Frank Tobian, Federica Lainati, Joachim Seybold, Terry C. Jones, Jörg Hofmann, Jilian A. Sacks, Frank P. Mockenhaupt, Claudia M. Denkinger European Respiratory Journal May 2021, 57 (5) 2004430; DOI: doi: https://doi.org/10.1183/13993003.04430-2020 https://doi.org/10.1183/13993003.04430-2020
The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2—Evaluation of the accuracy and ease-of-use Krüger LJ, Gaeddert M, Tobian F, Lainati F, Gottschalk C, et al. (2021) The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2—Evaluation of the accuracy and ease-of-use. PLOS ONE 16(5): e0247918. doi: https://doi.org/10.1371/journal.pone.0247918 https://doi.org/10.1371/journal.pone.0247918 |
Language
| English |
Producer
| Division of Clinical Tropical Medicine, Heidelberg University Hospital https://www.klinikum.uni-heidelberg.de/zentrum-fuer-infektiologie/sektion-klinische-tropenmedizin |
Production Date
| 2020-11-02 |
Production Location
| Heideberg and Berlin, Germany |
Contributor
| Data Collector : Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Tropical Medicine and International Health
Data Collector : Division of Clinical Tropical Medicine, Heidelberg University Hospital
Project Leader : Denkinger, Claudia Maria
Project Manager : Krüger, Lisa Johanna
Data Manager : Tobian, Frank |
Funding Information
| University Hospital Heidelberg
Forschung und Kunst Baden-Württemberg (MWK)
Foundation for Innovative New Diagnostics (FIND)
Charité - Universitätsmedizin Berlin |
Distributor
| Division of Clinical Tropical Medicine, Heidelberg University Hospital https://www.klinikum.uni-heidelberg.de/zentrum-fuer-infektiologie/sektion-klinische-tropenmedizin |
Depositor
| Division of Clinical Tropical Medicine, Heidelberg University Hospital |
Time Period
| Start Date: 2020-11-02 ; End Date: 2020-12-04 |
Date of Collection
| Start Date: 2020-11-02 ; End Date: 2020-12-04 |
Data Type
| Clinical Data |
Software
| R, Version: 4.0.3
REDCap, Version: 10.6.21 |
Related Dataset
| Krüger, Lisa J.; Gaeddert, Mary; Tobian, Frank; Lainati, Federica; Gottschalk, Claudius; Klein, Julian A.F.; Schnitzler, Paul; Kräusslich, Hans-Georg; Nikolai, Olga; Lindner, Andreas K.; Mockenhaupt, Frank P.; Seybold, Joachim; Corman, Victor M.; Drosten, Christian; Pollock, Nira; Knorr, Britta; Welker, Andreas; de Vos, Margaretha; Sacks, Jilian A.; Denkinger, Claudia M., 2021, "The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2 - Evaluation of the accuracy and ease-of-use [Research Data]", https://doi.org/10.11588/data/FSPQL4, heiDATA, V1 |