HDAMM-predictor: prediction of progression in asymptomatic myeloma patients (doi:10.11588/data/10092)

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Document Description

Citation

Title:

HDAMM-predictor: prediction of progression in asymptomatic myeloma patients

Identification Number:

doi:10.11588/data/10092

Distributor:

heiDATA

Date of Distribution:

2016-10-28

Version:

1

Bibliographic Citation:

Rème, Thierry; Emde, Martina; Seckinger, Anja; Hose, Dirk, 2016, "HDAMM-predictor: prediction of progression in asymptomatic myeloma patients", https://doi.org/10.11588/data/10092, heiDATA, V1

Study Description

Citation

Title:

HDAMM-predictor: prediction of progression in asymptomatic myeloma patients

Identification Number:

doi:10.11588/data/10092

Authoring Entity:

Rème, Thierry

Emde, Martina

Seckinger, Anja

Hose, Dirk

Producer:

Rème, Thierry

Emde, Martina

Seckinger, Anja

Hose, Dirk

Date of Production:

2016-02

Software used in Production:

3.1.1

Software used in Production:

2.14

Grant Number:

"CAMPSIMM" (01ES1103)

Grant Number:

"CLIOMMICS" (01ZX1309)

Grant Number:

SFB/TRR79

Grant Number:

"Heidelberger Konzept zur Optimierung der Diagnostik und Therapie des Multiplen Myeloms"

Grant Number:

"OverMyR"

Distributor:

heiDATA

Distributor:

heiDATA: Heidelberg Research Data Repository

Access Authority:

Priv.-Doz. Dr. med. Dr. biol. hom. Dirk Hose, Medizinische Klinik V, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, 49-6221-566140

Date of Deposit:

2016-10-26

Holdings Information:

https://doi.org/10.11588/data/10092

Study Scope

Keywords:

Medicine, Health and Life Sciences, Multiple myeloma, Risk prediction, Asymptomatic myeloma, Progression, Prognosis

Abstract:

The HDAMM-predictor is based on microarray gene expression and predicts the risk of progression from asymptomatic to symptomatic myeloma. It divides the patients in three groups, from low to high risk to progress. It was generated according to the method published by Rème et al. 2013. Gene expression profiles of 259 asymptomatic myeloma patients were used as trainingset.

Methodology and Processing

Sources Statement

Data Access

Citation Requirement:

Please do also cite the corresponding article:<br /> Seckinger A, Jauch A, Emde M, Beck, S, Mohr M, Granzow M, Hielscher T, Rème T, Schnettler R, Fard N, Hinderhofer K, Pyl P T, Huber W, Benes V, Marciniak-Czochra A, Pantesco V, Ho A D, Klein B, Goldschmidt H, Hillengass J, Hose D. Asymptomatic Multiple Myeloma - (Molecular) Background of Progression, Evolution and Prognosis. Manuscript under review.

Other Study Description Materials

Related Materials

ArrayExpress, Accession number E-MTAB-316 <a href="https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-316/">https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-316/</a>

Related Publications

Citation

Title:

Seckinger A, Jauch A, Emde M, Beck S, Mohr M, Granzow M, Hielscher T, Rème T, Schnettler R, Fard N, Hinderhofer K, Pyl P T, Huber W, Benes V, Marciniak-Czochra A, Pantesco V, Ho A D, Klein B, Goldschmidt H, Hillengass J, Hose D. Asymptomatic Multiple Myeloma - (Molecular) Background of Progression, Evolution and Prognosis. Manuscript under review.

Bibliographic Citation:

Seckinger A, Jauch A, Emde M, Beck S, Mohr M, Granzow M, Hielscher T, Rème T, Schnettler R, Fard N, Hinderhofer K, Pyl P T, Huber W, Benes V, Marciniak-Czochra A, Pantesco V, Ho A D, Klein B, Goldschmidt H, Hillengass J, Hose D. Asymptomatic Multiple Myeloma - (Molecular) Background of Progression, Evolution and Prognosis. Manuscript under review.

Citation

Title:

Seckinger A, Jauch A, Emde M, Beck S, Mohr M, Granzow M, Hielscher T, Rème T, Schnettler R, Fard N, Hinderhofer K, Pyl P T, Huber W, Benes V, Marciniak-Czochra A, Pantesco V, Ho A D, Klein B, Goldschmidt H, Hillengass J, Hose D. Asymptomatic Multiple Myeloma - (Molecular) Background of Progression, Evolution and Prognosis. Manuscript under review.

Bibliographic Citation:

Seckinger A, Jauch A, Emde M, Beck S, Mohr M, Granzow M, Hielscher T, Rème T, Schnettler R, Fard N, Hinderhofer K, Pyl P T, Huber W, Benes V, Marciniak-Czochra A, Pantesco V, Ho A D, Klein B, Goldschmidt H, Hillengass J, Hose D. Asymptomatic Multiple Myeloma - (Molecular) Background of Progression, Evolution and Prognosis. Manuscript under review.

Citation

Title:

Rème T, Hose D, Theillet C, Klein B. Modeling risk stratification in human cancer. Bioinformatics 2013;29:1149-57.

Identification Number:

10.1093/bioinformatics/btt124

Bibliographic Citation:

Rème T, Hose D, Theillet C, Klein B. Modeling risk stratification in human cancer. Bioinformatics 2013;29:1149-57.

Other Study-Related Materials

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Description.161027.pdf

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Notes:

application/pdf

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docval_1.1.4_gcrma.tar.gz

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application/x-gzip

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doc_by_val.pdf

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Documentation

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application/pdf

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HDAMM_function.R

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type/x-r-syntax

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parameter.Rdata

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application/x-rlang-transport

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Label:

README

Text:

Documentation

Notes:

text/plain; charset=US-ASCII