The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2 - Evaluation of the accuracy and ease-of-use [Research Data] (doi:10.11588/data/FSPQL4)

View:

Part 1: Document Description
Part 2: Study Description
Part 5: Other Study-Related Materials
Entire Codebook

(external link) (external link) (external link)

Document Description

Citation

Title:

The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2 - Evaluation of the accuracy and ease-of-use [Research Data]

Identification Number:

doi:10.11588/data/FSPQL4

Distributor:

heiDATA

Date of Distribution:

2021-04-30

Version:

1

Bibliographic Citation:

Krüger, Lisa J.; Gaeddert, Mary; Tobian, Frank; Lainati, Federica; Gottschalk, Claudius; Klein, Julian A.F.; Schnitzler, Paul; Kräusslich, Hans-Georg; Nikolai, Olga; Lindner, Andreas K.; Mockenhaupt, Frank P.; Seybold, Joachim; Corman, Victor M.; Drosten, Christian; Pollock, Nira; Knorr, Britta; Welker, Andreas; de Vos, Margaretha; Sacks, Jilian A.; Denkinger, Claudia M., 2021, "The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2 - Evaluation of the accuracy and ease-of-use [Research Data]", https://doi.org/10.11588/data/FSPQL4, heiDATA, V1

Study Description

Citation

Title:

The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2 - Evaluation of the accuracy and ease-of-use [Research Data]

Subtitle:

Evaluation of the accuracy and ease-of-use of PanBio

Identification Number:

doi:10.11588/data/FSPQL4

Authoring Entity:

Krüger, Lisa J. (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)

Gaeddert, Mary (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)

Tobian, Frank (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)

Lainati, Federica (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)

Gottschalk, Claudius (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)

Klein, Julian A.F. (Division of Clinical Tropical Medicine, Department of Infectious Diseases, University of Heidelberg, Heidelberg, Germany)

Schnitzler, Paul (Virology, Heidelberg University Hospital)

Kräusslich, Hans-Georg (Virology, Heidelberg University Hospital)

Nikolai, Olga (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Tropical Medicine and International Health)

Lindner, Andreas K. (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Tropical Medicine and International Health)

Mockenhaupt, Frank P. (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Tropical Medicine and International Health)

Seybold, Joachim (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Medical Directorate)

Corman, Victor M. (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Virology)

Drosten, Christian (Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Virology)

Pollock, Nira (Department of Laboratory Medicine, Boston Children’s Hospital)

Knorr, Britta (Department of Public Health Rhein Neckar Region)

Welker, Andreas (Department of Public Health Rhein Neckar Region)

de Vos, Margaretha (Foundation for Innovative New Diagnostics)

Sacks, Jilian A. (Foundation for Innovative New Diagnostics)

Denkinger, Claudia M. (Division of Clinical Tropical Medicine, Heidelberg University Hospital, Heidelberg)

Other identifications and acknowledgements:

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Tropical Medicine and International Health

Other identifications and acknowledgements:

Division of Clinical Tropical Medicine, Heidelberg University Hospital

Other identifications and acknowledgements:

Denkinger, Claudia Maria

Other identifications and acknowledgements:

Krüger, Lisa Johanna

Other identifications and acknowledgements:

Tobian, Frank

Producer:

Division of Clinical Tropical Medicine, Heidelberg University Hospital

Date of Production:

2020-09-28

Software used in Production:

R

Software used in Production:

REDCap

Distributor:

heiDATA

Distributor:

Division of Clinical Tropical Medicine, Heidelberg University Hospital

Access Authority:

Tobian, Frank

Depositor:

Division of Clinical Tropical Medicine, Heidelberg University Hospital

Study Scope

Keywords:

Medicine, Health and Life Sciences, SARS-CoV-2, Antigen-detecting, Covid-19, Diagnostics

Topic Classification:

Antigen-detecting diagnostics for SARS-CoV-2

Abstract:

This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab was performed for Ag-RDT testing. Routine swabs were nasopharyngeal (NP) or combined NP/oropharyngeal (OP) whereas the study-exclusive swabs were NP. To evaluate performance, sensitivity and specificity were assessed overall and in predefined sub analyses accordingly to cycle-threshold values, days of symptoms, disease severity and study site. In addition, further data from the participants were collected during interviews.

Date of Collection:

2020-09-28-2020-10-30

Kind of Data:

Clinical Data

Methodology and Processing

Sources Statement

Data Access

Notes:

Licensed under <a href='http://creativecommons.org/licenses/by-nc-nd/4.0/'>Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). &#160;<img src='https://i.creativecommons.org/l/by-nc-nd/4.0/80x15.png' alt='CC by sa' /></a>

Other Study Description Materials

Related Publications

Citation

Identification Number:

10.1101/2020.10.01.20203836

Bibliographic Citation:

Krüger LJ, Gaeddert M, Köppel L, Brümmer LE, Gottschalk C, Miranda IB, et al. Evaluation of the accuracy, ease of use and limit of detection of novel, rapid, antigen-detecting point-of-care diagnostics for SARS-CoV-2. medRxiv. 2020:2020.10.01.20203836.

Citation

Identification Number:

10.1101/2020.10.26.20219600

Bibliographic Citation:

Lindner AK, Nikolai O, Kausch F, Wintel M, Hommes F, Gertler M, et al. Head-to-head comparison of SARS-CoV-2 antigen-detecting rapid test with self-collected anterior nasal swab versus professional-collected nasopharyngeal swab. medRxiv. 2020:2020.10.26.20219600.

Citation

Identification Number:

10.1101/2021.03.17.21253076

Bibliographic Citation:

Head-to-head performance comparison of self-collected nasal versus professional-collected nasopharyngeal swab for a WHO-listed SARS-CoV-2 antigen-detecting rapid diagnostic test Julian A.F. Klein, Lisa J. Krüger, Frank Tobian, Mary Gaeddert, Federica Lainati, Paul Schnitzler, et al., medRxiv 2021.03.17.21253076; doi: https://doi.org/10.1101/2021.03.17.21253076

Other Study-Related Materials

Label:

Panbio.xlsx

Notes:

application/vnd.openxmlformats-officedocument.spreadsheetml.sheet