The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data] (doi:10.11588/data/KXTQTZ)

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The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]

doi:10.11588/data/KXTQTZ

heiDATA

2021-08-24

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Kohler, Stefan; Ndungwani, Rumbidzai; Burgert, Mark; Sibandze, Dumile; Matse, Sindy; Hettema, Anita, 2021, "The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]", https://doi.org/10.11588/data/KXTQTZ, heiDATA, V1

The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini [Research Data]

doi:10.11588/data/KXTQTZ

Kohler, Stefan (Heidelberg University, Faculty of Medicine and University Hospital, Heidelberg Institute of Global Health, Heidelberg, Germany and Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Social Medicine, Epidemiology and Health Economics, Berlin, Germany)

Ndungwani, Rumbidzai (Clinton Health Access Initiative, Mbabane, Eswatini)

Burgert, Mark (Clinton Health Access Initiative, Mbabane, Eswatini)

Sibandze, Dumile (Eswatini Ministry of Health, Mbabane, Eswatini)

Matse, Sindy (Eswatini Ministry of Health, Mbabane, Eswatini)

Hettema, Anita (Clinton Health Access Initiative, Mbabane, Eswatini)

heiDATA

Kohler, Stefan

https://doi.org/10.11588/data/KXTQTZ

Medicine, Health and Life Sciences

HIV treatment and prevention as well as other chronic disease care can require regular kidney function assessment based on a creatinine test. To assess the costs of creatinine testing in a public health care system, we conducted activity-based costing during a HIV pre-exposure prophylaxis (PrEP) demonstration project in the Hhohho region of Eswatini. Resource use was assessed by a laboratory technician and valued with government procurement prices, public sector salaries, and own cost estimates. Obtaining a blood sample in a clinic and performing a creatinine test in a high-throughput referral laboratory (> 660,000 blood tests, including > 120,000 creatinine tests, in 2018) were estimated to have cost, on average, $1.98 in 2018. Per test, $1.95 were variable costs ($1.38 personnel, ¢39 consumables, and ¢18 other costs) and ¢2.6 were allocated semi-fixed costs (¢1.1 laboratory equipment, ¢0.85 other, ¢0.45 consumables, and ¢1.3 personnel costs). Simulating different utilization of the laboratory indicated that semi-fixed costs of the laboratory (e.g., equipment purchase or daily calibration of the chemistry analyzer) contributed less than variable costs (e.g., per-test personnel time and test reagents) to the average creatinine test cost when certain minimum test numbers can be maintained. Our findings suggest, first, lower creatinine testing costs than previously used in cost and cost-effectiveness analyses of HIV services and, second, that investment in laboratory equipment imposed a relatively small additional cost on each performed test in the high-throughput referral laboratory.

2017-2018

Kohler S, Ndungwani R, Burgert M, Sibandze D, Matse S, Hettema A. The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini. AIDS and Behavior 2021.

10.1007/s10461-021-03432-4

Kohler S, Ndungwani R, Burgert M, Sibandze D, Matse S, Hettema A. The costs of creatinine testing in the context of a HIV pre-exposure prophylaxis demonstration project in Eswatini. AIDS and Behavior 2021.

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Costing tool and data

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