Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset] (doi:10.11588/data/10028)

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Part 2: Study Description
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Document Description

Citation

Title:

Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset]

Identification Number:

doi:10.11588/data/10028

Distributor:

heiDATA

Date of Distribution:

2014-10-15

Version:

4

Bibliographic Citation:

Jerabek, Hansjörg; Tark-Dame, Mariliis; Manders, Erik M. M.; Heermann, Dieter W.; van Driel, Roel, 2014, "Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset]", https://doi.org/10.11588/data/10028, heiDATA, V4

Study Description

Citation

Title:

Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset]

Identification Number:

doi:10.11588/data/10028

Authoring Entity:

Jerabek, Hansjörg (Institute for Theoretical Physics)

Tark-Dame, Mariliis (Institute for Theoretical Physics)

Manders, Erik M. M. (Institute for Theoretical Physics)

Heermann, Dieter W. (Institute for Theoretical Physics)

van Driel, Roel (Institute for Theoretical Physics)

Producer:

Jerabek, Hansjörg

Tark-Dame, Mariliis

Manders, Erik M. M.

Heermann, Dieter W.

van Driel, Roel

Date of Production:

2014-09-01

Distributor:

heiDATA

Distributor:

HeiDATA: Heidelberg Research Data Repository

Access Authority:

Heermann, Dieter W.

Date of Deposit:

2014-10-14

Holdings Information:

https://doi.org/10.11588/data/10028

Study Scope

Keywords:

Medicine, Health and Life Sciences, Physics, Polymer, Chromatin, DNA, Chromatin folding, CTCF, Cohesin, Chromatin looping, BFM, Monte-Carlo simulations, Dynamic Loop model

Abstract:

Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction.

Geographic Coverage:

Germany, Netherlands

Methodology and Processing

Sources Statement

Data Access

Access Authority:

Prof. Dr. Dieter W. Heermann, Institute for Theoretical Physics, University of Heidelberg, Philosophenweg 12, 69120 Heidelberg, Germany

Other Study Description Materials

Related Publications

Citation

Title:

Tark-Dame M, Jerabek H, Manders EMM, Heermann DW, van Driel R (2014): Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling. PLoS Comput Biol 10(10): e1003877.

Identification Number:

doi:10.1371/journal.pcbi.1003877

Bibliographic Citation:

Tark-Dame M, Jerabek H, Manders EMM, Heermann DW, van Driel R (2014): Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling. PLoS Comput Biol 10(10): e1003877.

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Control_FISH_20140901.txt

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CTCFkd_FISH_20140901.txt

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CTCF_Rad21kd_FISH_20140901.txt

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globules_7.zip

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